Sleep Disorders (SDs) precede motor symptoms of Parkinson’s disease (PD), suggesting an early effect of disease processes on sleep control neurons. These nucleus-specific differential effects suggest previously unappreciated, mechanistic underpinnings of SDs’ prodromal PD appearance in PD, and we
hypothesize that in the prodromal phase of PD, the early form of α-synuclein compromises sleep-control neurons. https://doi.org/10.21203/rs.3.rs-134060/v1