Fecal Transplants (FMT)

Gut Microbiota Dysbiosis: Triggers, Consequences, Diagnostic and Therapeutic Options

Butyrate, Fecal Transplants (FMT), Gut Dysbiosis, Gut Microbiota, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

The global incidence of numerous immune-mediated, metabolic, neurodegenerative, and psychiatric diseases is steadily increasing [1,2,3]. The increased morbidity of human populations makes them more vulnerable to additional burdens, including infectious diseases. For example, the mortality rate of diabetics infected with the original variant of the SARS Co-2 virus was about twice that of the general […]

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Gastrointestinal Microbiome and Neurologic Injury

Butyrate, Constipation, ENS, Fecal Transplants (FMT), Gut Dysbiosis, Gut Microbiota, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

: Communication between the enteric nervous system (ENS) of the gastrointestinal (GI)tract and the central nervous system (CNS) is vital for maintaining systemic homeostasis. Intrinsicand extrinsic neurological inputs of the gut regulate blood flow, peristalsis, hormone release, andimmunological function. The health of the gut microbiome plays a vital role in regulating the overallfunction and well-being

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The second brain in Parkinson’s disease: fact or fantasy?

Fecal Transplants (FMT), Gut Microbiota, Probiotics, Prebiotics and Symbiotics /

We have briefly expressed three components that are significant in promoting the complex involvement of the gut within PD. Thorough research has looked into the physiology and symptoms of PD, with further exploration into the gut microbiota a crucial step in truly understanding the disease process. Adopting strategies to ensure stable, healthy microbial consumption along

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The Role of Dysbiosis in Neurological Disorders

Biomarkers, Butyrate, Fecal Transplants (FMT), Gut Dysbiosis, Gut Microbiota, Gut Permeability / Leaky Gut, Gut-Brain axis, Metabolites, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

The gut brain axis is a system of bi-directional communication. When the delicate balance of the microbiome is disrupted, the resulting dysbiosis can be a factor in the development of neurological disorders, including Alzheimer’s Disease (AD), Parkinson’s Disease (PK), and Multiple Sclerosis (MS). One major player in the gut brain axis are short-chain fatty acids

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Gut Microbiota Regulation and Their Implication in the Development of Neurodegenerative Disease

Fecal Transplants (FMT), Gut Microbiota, Gut Permeability / Leaky Gut, Gut-Brain axis, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids, Vagal Nerve /

In recent years, human gut microbiota have become one of the most promising areasof microorganism research; meanwhile, the inter-relation between the gut microbiota and varioushuman diseases is a primary focus. As is demonstrated by the accumulating evidence, the gastrointestinal tract and central nervous system interact through the gut–brain axis, which includesneuronal, immune-mediated and metabolite-mediated pathways.

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Effect of Fiber and Fecal Microbiota Transplantation Donor on Recipient Mice Gut Microbiota

Fecal Transplants (FMT), Gut Microbiota, Probiotics, Prebiotics and Symbiotics /

Both fecal microbiota transplantation (FMT) and dietary fiber intervention were verified as effective ways to manipulate the gut microbiota, whereas little is known about the influence of the combined methods on gut microbiota. Here, we constructed “non-industrialized” and “industrialized” gut microbiota models to investigate the donor effect of FMT and diet effect in shaping the

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Genetic and environmental factors in Alzheimer’s and Parkinson’s diseases and promising therapeutic intervention via fecal microbiota transplantation

Biomarkers, Fecal Transplants (FMT), Gut Dysbiosis, Gut Microbiota, Gut Permeability / Leaky Gut, Gut-Brain axis /

The gut microbiota provides potential therapeutic targets that can be regulated as new interventions for neurodegenerative diseases. In this review, we discuss genetic and environmental risk factors for neurodegenerative diseases, summarize the communication among the components of the microbiota-gut-brain axis, and discuss the treatment strategy of fecal microbiota transplantation (FMT). FMT is a promising treatment

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Gut brain axis: an insight into microbiota role in Parkinson’s disease

Biomarkers, Fecal Transplants (FMT), Gut Dysbiosis, Gut Microbiota, Gut Permeability / Leaky Gut, Gut-Brain axis, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics /

The gut-brain axis is a two-way communication system, which explains how through the vagus nerve, the gut microbiota can affect the central nervous system (CNS), including brain functions related to the ENS, as well as how CNS can alter various gut secretions and immune responses. As a result, this dysbiosis or alteration in gut microbiota

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Fecal Microbiota Transplantation Exerts a Protective Role in MPTP-Induced Parkinson’s Disease via the TLR4/PI3K/AKT/NF-κB Pathway Stimulated by α-Synuclein

A-Synuclein, Fecal Transplants (FMT), Parkinson's Disease /

A mouse model with PD was established via injection of MPTP. Normal or MPTP-induced PD like animals were treated with FMT from healthy normal mice. Pole test and traction test were performed to examine the effects of FMT on motor function of PD mice. Fecal SCFAs were assessed by gas chromatography-mass spectrometry. The α-syn level in

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Fecal Microbiota Transplantation: A Microbiome Modulation Technique for Alzheimer’s Disease

Fecal Transplants (FMT), Parkinson's Disease /

Microbiota-targeted interventions such as personalized diet, probiotics, or fecal microbiota transplantation (FMT) might represent a potential therapeutic option for AD. This review article discusses the procedure of FMT and its possible side effects on the recipient’s body. In addition, we review the role of FMT in the context of its application in various nervous system-related

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