April 2022

Aging Microbiota-Gut-Brain Axis in Stroke Risk
and Outcome

Gut Dysbiosis, Gut Microbiota, Gut-Brain axis, Probiotics, Prebiotics and Symbiotics, Stroke /

The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut microbes and theirhost. Many environmental and host-related factors affect the gut microbiota. Dysbiosis is defined as compositional andfunctional alterations of the gut microbiota that contribute to the pathogenesis, progression and treatment responses todisease. Dysbiosis occurs when perturbations of microbiota composition and function exceed the ability […]

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Phenoconversion Risk Factors in Rapid Eye Movement Sleep Behavior Disorder

Biomarkers, Enviromental, iRBD, Parkinson's Disease, Pesticides, Pre-PD /

A multicenter cohort of idiopathic/isolated rapid eye movement sleep behavior disorder (iRBD) was studied to determine any predictive factors for α-synuclein–related neurodegenerative illnesses. At the start of the study, patients with iRBD from 12 different sites were given a complete assessment for potential environmental and lifestyle risk factors using a standardized questionnaire. Patients were then

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Modulation of gut health using probiotics: the role of probiotic effector molecules

Gut Microbiota, Gut Permeability / Leaky Gut, Gut-Brain axis, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Probiotics affect intestinal metabolism and play a crucial role in gut homeostasis. Studies on probiotic effector molecules—bacteriocins, peptidoglycan, teichoic acid, exopolysaccharides, secretory proteins, and short-chain fatty acids—describe their effect on the gut barrier; immune and nervous system; and gut microbiota. However, the detailed mechanism of how the intestinal microbiota changes after the intervention of effector

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Self-reported periodontitis and C-reactive protein in
Parkinson’s disease: a cross-sectional study of
two American cohorts

endondonics, Oral Microbiome, Parkinson's Disease, Periodontitis, Root Canal /

Periodontitis triggers systemic repercussions, such as elevated levels of high-sensitive C-reactive protein (hs-CRP). This has neverbeen studied within Parkinson’s Disease (PD). The aim of this study is to compare hs-CRP levels of self-reported periodontitis casesversus cases without periodontitis in PD patients. Data from the National Health and Nutrition Examination Survey (2015–2016 and2017–2018 waves) were analyzed.

Self-reported periodontitis and C-reactive protein in
Parkinson’s disease: a cross-sectional study of
two American cohorts Read More »

Fermented brown rice beverage distinctively modulates the gut microbiota in Okinawans with Metabolic Syndrome: a randomized controlled trial

Butyrate, Diet and Exercise, Fermented Foods, Gut Dysbiosis, Gut Microbiota, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Accumulating evidence to date suggests that brown rice is superior to white rice in regards to its beneficial impact on a number of risk factors of the metabolic syndrome (MetS). However, little is known about the influence of fermented brown rice beverage on the gut microbiota in humans. We therefore hypothesized that its impact would

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Environmental factors shaping the gut microbiome in a Dutch population

Diet and Exercise, Enviromental, Gut Dysbiosis, Gut Microbiota, Metabolites, Parkinson's Disease /

The gut microbiome is associated with diverse diseases1,2,3, but a universal signature of a healthy or unhealthy microbiome has not been identified, and there is a need to understand how genetics, exposome, lifestyle and diet shape the microbiome in health and disease. Here we profiled bacterial composition, function, antibiotic resistance and virulence factors in the

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Fermented Foods, Health and the Gut Microbiome

Fermented Foods, Gut Microbiota, Metabolites, Probiotics, Prebiotics and Symbiotics /

Fermented foods have been a part of human diet for almost 10,000 years, and their levelof diversity in the 21st century is substantial. The health benefits of fermented foods have beenintensively investigated; identification of bioactive peptides and microbial metabolites in fermentedfoods that can positively affect human health has consolidated this interest. Each fermented foodtypically hosts

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Probiotics in Health and Disease: A Review of Emerging
Evidence of Potential Benefits and Harm

Gut Dysbiosis, Gut Microbiota, Gut-Brain axis, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics /

Emerging multi-drug resistant pathogens are the main driving force behind the efforts to find analternative treatment approach such as probiotics. Probiotics are considered living drugs that can reduce theconsumption of conventional antibiotics and improve human and animal health. Particularly, bacterial originprobiotics became increasingly popular during the last two decades as a result of the continuously

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Evidence of Potential Benefits and Harm Read More »

Linking circadian rhythms to microbiome-gut-brain axis in aging-associated neurodegenerative diseases

ENS, Gut Dysbiosis, Gut Microbiota /

Emerging evidence suggests that both disruption of circadian rhythms and gut dysbiosis are closely related to aging-associated neurodegenerative diseases. Over the last decade, the microbiota-gut-brain axis has been an emerging field and revolutionized studies in pathology, diagnosis, and treatment of neurological disorders. Crosstalk between the brain and gut microbiota can be accomplished via the endocrine,

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Gut–Brain Cross Talk: Microbiome
and Micronutrients

Butyrate, Diet and Exercise, Gut Dysbiosis, Gut Microbiota, Gut-Brain axis, Metabolites, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

A good diet may deliver micronutrients such as vitamins A, B6, B12, C,and D and minerals such as iron, copper, zinc, and selenium that have beenimplicated to have key roles for supporting immunity with reducing host infections.Most studies have shown that once the subject was infected, the immune system willbe enhanced, which will require high

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and Micronutrients Read More »