Diet and Exercise

Western and ketogenic diets in neurological disorders: can you tell the difference?

Diet and Exercise, Metabolites, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics /

The prevalence of obesity tripled worldwide between 1975 and 2016, and it is projected that half of the US population will be overweight by 2030. The obesity pandemic is attributed, in part, to the increasing consumption of the high-fat, high-carbohydrate Western diet, which predisposes to the development of the metabolic syndrome and correlates with decreased […]

Western and ketogenic diets in neurological disorders: can you tell the difference? Read More »

Identification of components of turmeric as potential therapeutic agents to
slow the progression of neurodegeneration in Parkinson’s disease

A-Synuclein, Diet and Exercise, Vitamins / Supplements / Nutraceuticals /

Parkinson’s disease (PD) is a neurological disorder associated with severe loss of dopaminergic neurons inthe substantia nigra. These neurons are particularly vulnerable due to increased iron and decreasedantioxidant levels with aging, constant exposure to reactive oxygen species (ROS), and the presence ofneurotoxic compounds. A literature review was compiled and published, in which we postulate that

Identification of components of turmeric as potential therapeutic agents to
slow the progression of neurodegeneration in Parkinson’s disease Read More »

Low-carbohydrate and ketogenic diets: a scoping review of neurological and inflammatory outcomes in human studies and their relevance to chronic pain

Diet and Exercise /

Dietary restriction of carbohydrates has been demonstrated to be beneficial for nervous system dysfunction in animal models and may be beneficial for human chronic pain. The purpose of this review is to assess the impact of a low-carbohydrate/ketogenic diet on the adult nervous system function and inflammatory biomarkers to inform nutritional research for chronic pain.

Low-carbohydrate and ketogenic diets: a scoping review of neurological and inflammatory outcomes in human studies and their relevance to chronic pain Read More »

Fermented brown rice beverage distinctively modulates the gut microbiota in Okinawans with Metabolic Syndrome: a randomized controlled trial

Butyrate, Diet and Exercise, Fermented Foods, Gut Dysbiosis, Gut Microbiota, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Accumulating evidence to date suggests that brown rice is superior to white rice in regards to its beneficial impact on a number of risk factors of the metabolic syndrome (MetS). However, little is known about the influence of fermented brown rice beverage on the gut microbiota in humans. We therefore hypothesized that its impact would

Fermented brown rice beverage distinctively modulates the gut microbiota in Okinawans with Metabolic Syndrome: a randomized controlled trial Read More »

Environmental factors shaping the gut microbiome in a Dutch population

Diet and Exercise, Enviromental, Gut Dysbiosis, Gut Microbiota, Metabolites, Parkinson's Disease /

The gut microbiome is associated with diverse diseases1,2,3, but a universal signature of a healthy or unhealthy microbiome has not been identified, and there is a need to understand how genetics, exposome, lifestyle and diet shape the microbiome in health and disease. Here we profiled bacterial composition, function, antibiotic resistance and virulence factors in the

Environmental factors shaping the gut microbiome in a Dutch population Read More »

Gut–Brain Cross Talk: Microbiome
and Micronutrients

Butyrate, Diet and Exercise, Gut Dysbiosis, Gut Microbiota, Gut-Brain axis, Metabolites, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

A good diet may deliver micronutrients such as vitamins A, B6, B12, C,and D and minerals such as iron, copper, zinc, and selenium that have beenimplicated to have key roles for supporting immunity with reducing host infections.Most studies have shown that once the subject was infected, the immune system willbe enhanced, which will require high

Gut–Brain Cross Talk: Microbiome
and Micronutrients Read More »

Inulin fructans in diet: Role in gut homeostasis, immunity, health outcomes and potential therapeutics

Diet and Exercise, Gut Dysbiosis, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Inulin consumption in both humans and animal models is recognized for its prebiotic action with the most consistent change that lies in enhancing the growth and functionality of Bifidobacterium bacteria, as well as its effect on host gene expression and metabolism. Further, inulin-type fructans are utilized in the colon by bacterial fermentation to yield short-chain fatty acids (SCFAs), which play

Inulin fructans in diet: Role in gut homeostasis, immunity, health outcomes and potential therapeutics Read More »

Reducing neuroinflammation via therapeutic compounds and lifestyle to prevent or delay progression of Parkinson’s disease.Prevention of neuroinflammation in Parkinson’s disease

Diet and Exercise, Fasting, Parkinson's Disease, Therapies /

Parkinson’s disease (PD) is the second most common age-associated neurodegenerative disorder and is characterized by progressive loss of dopamine neurons in the substantia nigra. Peripheral immune cell infiltration and activation of microglia and astrocytes are observed in PD, a process called neuroinflammation. Neuroinflammation is a fundamental response to protect the brain but, when chronic, it

Reducing neuroinflammation via therapeutic compounds and lifestyle to prevent or delay progression of Parkinson’s disease.Prevention of neuroinflammation in Parkinson’s disease Read More »

Facts and controversies regarding oral health in Parkinson’s disease:
A case-control study in Spanish patients

Diet and Exercise, endondonics, Oral Microbiome, Parkinson's Disease, Pre-PD, Root Canal /

Oral disorders are frequent in PD. Good knowledge of these alterations will allow us to design a specific preventive protocol. Some oral alterations may be a sign of diagnostic alert or progression of PD. CLICK TO REVIEW

Facts and controversies regarding oral health in Parkinson’s disease:
A case-control study in Spanish patients Read More »

Effects of a Ketogenic Diet on Symptoms, Biomarkers, Depression, and Anxiety in Parkinson’s Disease: A Case Study

Diet and Exercise, Parkinson's Disease /

The ketogenic diet has grown in popularity as an alternative or adjunct to medication therapy for Parkinson’s disease (PD) and other neurodegenerative diseases (NDD). Traditional medication therapies often fail to produce desired improvements in PD symptoms and can have little or no effect on symptoms of depression and anxiety that often accompany a PD diagnosis. We

Effects of a Ketogenic Diet on Symptoms, Biomarkers, Depression, and Anxiety in Parkinson’s Disease: A Case Study Read More »