March 2021

Parkinson’s Disease: Possible Mechanisms for Nutritional Approaches

Diet and Exercise, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics /

Parkinson’s disease (PD) is among the most common chronic neurodegenerative conditions, affecting 1% of those over 60 years of age, and involves motor and non-motor impairments. Alterations in normal physiology may become apparent years – in some cases, 10–20 years – before established diagnostic criteria are met. Thus, better clinical outcomes may result when practitioners […]

Parkinson’s Disease: Possible Mechanisms for Nutritional Approaches Read More »

Excessive Muscle Activity Increases Over Time in Idiopathic REM Sleep Behavior Disorder

iRBD /

Excessive tonic and phasic EMG activity during REM sleep increases over time in subjects with idiopathic RBD. This finding suggests that, in subjects with idiopathic RBD, there is an underlying progressive pathologic process damaging the brainstem structures that modulate REM sleep. CLICK TO REVIEW

Excessive Muscle Activity Increases Over Time in Idiopathic REM Sleep Behavior Disorder Read More »

Objective sleep data as predictors of cognitive decline in dementia with Lewy Bodies and Parkinson’s disease

Dementia - Lewy Bodies, iRBD, Pre-PD /

Our data suggests that PSG data can be useful in predicting cognitive decline in PD but not in DLB patients. In PD patients, an RBD diagnosis is predictive of cognitive deterioration, confirming the notion that this non-motor symptom relates to a malignant sub-type. Tonic excessive muscular activity, but not other RBD features, had predictive value in

Objective sleep data as predictors of cognitive decline in dementia with Lewy Bodies and Parkinson’s disease Read More »