May 2021

The microbiota-gut-brain axis and Alzheimer disease. From dysbiosis to neurodegeneration: focus on the central nervous system glial cells

Gut Dysbiosis, Gut-Brain axis /

Much evidence has accumulated over the past decade in favor of a significant association between dysbiosis, neuroinflammation and neurodegeneration. Presently, the pathogenetic mechanisms triggered by molecules produced by the altered microbiota, also responsible for the onset and evolution of Alzheimer Disease will be described. Our attention will be focused on the role of astrocytes and […]

The microbiota-gut-brain axis and Alzheimer disease. From dysbiosis to neurodegeneration: focus on the central nervous system glial cells Read More »

Does modern research validate the ancient wisdom of gut flora and brain connection?

Gut-Brain axis /

Both animal and human studies evaluating the role of gut dysbiosis on various neurological and neurosurgical diseases, published in peer-reviewed journals, were reviewed. Current studies do not provide conclusive evidence of a direct origin of CNS disorders from gut dysbiosis, but a possible modulatory role of gut microbiota in certain neurological disorders has been implicated.

Does modern research validate the ancient wisdom of gut flora and brain connection? Read More »

Diet-Microbiota-Brain Axis in Alzheimer’s Disease

Gut Microbiota /

A strong association exists between lifestyle factors and AD prevalence wherein unhealthy dietary factors have been linked to neurodegeneration. Specific prudent dietary patterns might help in preventing or delaying AD progression by affecting β-amyloid production and tau processing and regulating AD-associated inflammation, metabolism and oxidative stress, plausibly via modulating gut microbiota. CLICK TO REVIEW

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Systematic video-analysis of motor events during REM sleep in idiopathic REM sleep behavior disorder, follow-up and DAT-SPECT

Biomarkers, iRBD /

Patients with higher amounts of violent Motor Events had a greater risk of phenoconversion; therefore, their role as a predictor should be considered. Additionally, ME were associated with nigrostriatal degeneration, according to DAT-SPECT. These findings indicate that the degree of the clinical severity of motor manifestations in iRBD reflects the severity of the disease. CLICK

Systematic video-analysis of motor events during REM sleep in idiopathic REM sleep behavior disorder, follow-up and DAT-SPECT Read More »