A Review of Literature on the Relationship Between
Oral Microbiota and Rheumatoid Arthritis

Periodontal disease (PDD) and rheumatoid arthritis (RMA) share comparative pathophysiological pathways like ongoing
aggravation with resorption of the proximal bone in immunologically delicate hosts; However, PDD has a notable bacteriological etiology, and the cause of RMA remains unknown. According to some reports, an infectious agent in a vulnerable host may be the cause of RMA and dental microorganisms, in particular, periodontal bacteria, may be the causative
agent of RMA infectious agents (mainly Porphyromonas gingivalis). PDD has been demonstrated to be more normal and
extreme in patients with RMA showing a connection between the two illnesses. Antibodies against periodontal microbes
have been found, and different examinations have discovered bacterial DNA in the serum and synovial liquid of patients
with RMA and researched conceivable transmission courses, the presence of periodontal bacterial DNA. Overall, there is
no question that RMA and PDD share comparative neurotic components, and there is generous proof for a connection
between the two diseases, however more examination, including exploratory models, is expected to show the copathogenicity of oral microscopic organisms. CLICK TO REVIEW