Under pathologic conditions, cellular accumulation of misfolded α-synuclein oligomers and aggregates are observed in a group of neurodegenerative diseases called synucleinopathies. The mechanisms of how α-synuclein protein takes part in the neurodegeneration process and physiologic roles of the protein have not been fully elucidated yet. It’s important to unravel the secrets of this protein and understand its behaviours in order to improve existing treatment protocols and also to develop new and more effective treatments for Parkinson’s Disease. CLICK TO REVIEW