Background: Over the last three decades, consumption of total and saturated fat has steadily declined in Western diets as a proportion of calories intake. At the same time, omega (ω)-6 fatty acid intake has risen at the expense of ω-3 fatty acids, resulting in an ω-6/ω-3 ratio of 20:1 or higher. Scope and approach: The […]
Background: Parkinson’s disease is a common neurologic ailment that causes tremor and bradykinesia. The prevalenceof Parkinson’s disease is estimated to be 1–2 in 1000, affecting about 1% of the population over the age of 60 years. Theobjective of this study was to find the frequency of Non-Motor Symptoms in patients with Parkinson’s Disease (PD) andits
Non-Motor Symptoms and Their Associated Factors in Parkinson’s Disease Read More »
Current study provides a valuable and highly informative dataset of EV-associated sncRNAsfrom plasma of iRBD and PD patients. We identified miRNA signature features that could serve asminimally-invasive, blood-based surveillance biomarkers for distinguishing iRBD or PD from healthyindividuals with high sensitivity, specificity, and accuracy. CLICK TO REVIEW
Parkinson’s disease, a neurodegenerative disease, is caused by dopaminergic neurons death and accompanied byrigidity, and postural instability, as well as bradykinesia. The cause of these neurons’ death is still unclear. Since thedopaminergic neurons couldn’t regenerate, therefore Parkinson’s disease couldn’t be cured. Thus, over the pastdecades, significant effort has been made to explore the etiology of
Overview on Parkinson’s disease: pathophysiology, and experimental models Read More »
It has been proven that physical exercise improves cognitive function and memory, hasan analgesic and antidepressant effect, and delays the aging of the brain and the development ofdiseases, including neurodegenerative disorders. There are even attempts to use physical activity inthe treatment of mental diseases. The course of most diseases is strictly associated with oxidativestress, which
Physical Activity vs. Redox Balance in the Brain: Brain Health, Aging and Diseases Read More »
Parkinson’s Disease (PD) is a neurodegenerative disease, leading to motor and nonmotor complications. Autonomic alterations, including gastrointestinal symptoms, precede motordefects and act as early warning signs. Chronic exposure to dietary, environmental heavy metalsimpacts the gastrointestinal system and host-associated microbiome, eventually affecting the centralnervous system. The correlation between dysbiosis and PD suggests a functional and bidirectionalcommunication
The gut microbiota (GM) is formed by millions of microorganisms present in the gastrointestinal tract, especially in the colon. This intestinal homeostasis can be triggered by the union of a good diet, and even recent studies have suggested that aerobic physical training can modify its composition. Objective:To analyze the influence of healthy eating added to
Gut microbiota related to nutrition and physical activity: an integrative review Read More »
Emerging evidence indicates that probiotics can influence the gut–brain axis to ameliorate somatic and behavioral symptoms associated with brain disorders. However, whether probiotics have effects on the electrophysiological activities of individual neurons in the brain has not been evaluated at a single-neuron resolution, and whether the neuronal effects of probiotics depend on the gut microbiome
Homeostatic regulation of neuronal excitability by probiotics in male germ-free mice Read More »
Parkinson’s disease (PD) is one of the major progressive neurological disorders. It occurs due to a low level of achemical substance in the brain known as Dopamine, which controls the muscle movements of the body. In many cases, PDoccurs due to a low level of dopamine. PD generally appears in persons between the ages of
Background: The aim of the study was to evaluate the effect of Tai Chi on functional mobility, balance and falls in Parkinson’s disease. Materials and methods: A comprehensive literature search was conducted to identify the systematic reviews and meta-analyses up to the end of October 2021. 601 studies were identified, and 16 of them were included in