Living with a neurological condition like Parkinson’s disease, autism, or chronic stress is hard enough. It can feel overwhelming to dig through all the science to find a probiotic you trust enough to add to your routine. click to review
Searching for a Gut-Brain probiotic with real science behind it? Read More »
Both fecal microbiota transplantation (FMT) and dietary fiber intervention were verified as effective ways to manipulate the gut microbiota, whereas little is known about the influence of the combined methods on gut microbiota. Here, we constructed “non-industrialized” and “industrialized” gut microbiota models to investigate the donor effect of FMT and diet effect in shaping the
: Within the last two decades tremendous efforts in biomedicine have been undertaken tounderstand the interplay of commensal bacteria living in and on our human body with our ownhuman physiology. It became clear that (1) a high diversity especially of the microbial communitiesin the gut are important to preserve health and that (2) certain bacteria
Microbiota in Health and Disease—Potential Clinical Applications Read More »
Dr. Michael Kaplitt, a professor of neurological surgery at Weill Cornell Medicine and a longtime leader in developing cutting-edge surgical therapies for movement disorders, leads a team that has been awarded a three-year, $8.9 million grant from the Aligning Science Across Parkinson’s (ASAP) initiative. The grant will fund an ambitious and innovative multi-institutional collaborative effort to study
$9M Grant Funds Study of Gut-Brain Connection in Parkinson’s Disease Read More »
Akome’s AKO004 psychedelic drug formulation, for use in the treatment of Parkinson’s disease, is a composition comprising the psychedelic compound N,N-dimethyltryptamine (DMT) and, a specifically chosen, naturally occurring plant bioactive. Initial data analysis indicates that the AKO004 composition is safe and efficacious for use, and presents many positive properties which may counter or mitigate neurodegeneration
Alpha-synuclein(α-Syn) is an intracellular protein which is constantly synthesized and degraded underphysiological conditions. Abnormal aggregation of this protein within neuron is associated with severalneurodegenerative disorders, including Parkinson’s disease. Although the exact mechanism of initiation ofaggregation and misfolding pathway of a-Syn is yet to be discovered; it’s mechanism of spreading throughinterconnected neuronal networks has taken acompelling
Plasma GSH was associated with pPD probability trajectories; therefore, it might assist in the identification of individuals who are likely to reach the threshold for pPD diagnosis more rapidly. CLICK TO REVIEW
Plasma Glutathione and Prodromal Parkinson’s Disease Probability Read More »
The blood-brain barrier (BBB) is a fundamental component of the central nervous system(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain microenvironment by controlling the passage of substances and regulating the trafficking of immune cellsbetween the blood and the brain. The BBB is primarily composed of highly specialized microvascular
Gastrointestinal dysfunction is a prominent nonmotor feature of Parkinson’s disease and dysfunction can be found along the entire length of the gastrointestinal tract. The enteric nervous system is clearly involved in Parkinson’s disease. Whether it is the initial source of pathology is still a source of controversy. There also is growing recognition of the role
Gastrointestinal Dysfunction in Parkinson’s Disease Read More »
Our understanding of dysfunction of the gastrointestinal system in patients with Parkinson’s disease has increased substantially in the past decade. The entire gastrointestinal tract is affected in these patients, causing complications that range from oral issues, including drooling and swallowing problems, to delays in gastric emptying and constipation. Additionally, small intestinal bacterial overgrowth and Helicobacter
Gastrointestinal dysfunction in Parkinson’s disease. Read More »