Diet and Exercise

Disease Modifying Potential of Functional Foods for Neurodegenerative Disorders: Status Update on Regulatory Compliance

Diet and Exercise, Gut Dysbiosis, Gut Microbiota, Gut Permeability / Leaky Gut /

Progressive loss of functional neurons is typically characterized as neurodegeneration. This is particularly pronounced during aging and results in debilitating conditions such as Parkinson’s disease and Alzheimer’s disease. Symptoms appear typically after 70–80% neuronal loss, resulting in irreversible damage. Several drugs have been clinically approved but they only alleviate symptoms and additionally lead to undesirable […]

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Ketogenic Diet and Health

Diet and Exercise, Fasting /

In recent years, emerging evidence suggests KD’s may also have therapeutic benefits for some cancers and for neurological conditions such asAlzheimer’s disease, Parkinson’s’ disease, multiple sclerosis, traumatic brain injury, and spinal cord injury. Finally, as the physiological mechanisms by which a KD operates become increasingly understood, we speculate that several other health conditions (e.g., autism,

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Dietary bioactive compounds as modulators of mitochondrial function

Diet and Exercise, Mitochondria /

In the last years, it has been consistently reported that the modulation of mitochondrial function represents one of the mechanisms behind the bioactive compounds-dependent health improvements. In this review, we focus on gathering, summarizing, and discussing the evidence that supports the effect of dietary bioactive compounds on mitochondrial activity and the relation of these effects

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MIND and Mediterranean Diets Associated with Later Onset of Parkinson’s Disease

Diet and Exercise /

This cross-sectional study found a strong correlation between age of onset of PD and dietary habits, suggesting that nutritional strategies may be an effective tool to delay PD onset. Further studies may help to elucidate potential nutrition-related sex-specific pathophysiological mechanisms and differential prevalence rates in PD. CLICK TO REVIEW

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Motor Dysfunction in REM Sleep Behavior Disorder: A Rehabilitation Framework for Prodromal Synucleinopathy

A-Synuclein, Dementia - Lewy Bodies, Diet and Exercise, iRBD, Pre-PD /

The proposed rehabilitation framework for iRBD includes early exercise-based interventions of aerobic exercise, progressive resistance training, and multimodal exercise with rehabilitation consultations to address exercise prescription, progression, and monitoring. This rehabilitation framework may be used to implement neuroprotective, multidisciplinary, and proactive clinical care in people with a high likelihood of conversion to PD, dementia with

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Supplementation of regular diet with medium-chain triglycerides for neuroprotective effects

Diet and Exercise, Short Chain Fatty Acids /

This review summarizes currently available research on the effects and revealed mechanisms of using MCTs as a supplement to standard feed/diet without concomitant reduction of carbohydrate intake, highlighting open questions and potential considerations.

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Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids

Diet and Exercise, Gut Microbiota, Short Chain Fatty Acids /

This review specifically highlights the regulatory functions of DF and SCFAs in the immune system with a focus on major innate and adaptive lymphocytes. Current information regarding how SCFAs regulate innate lymphoid cells, T helper cells, cytotoxic T cells, and B cells and how these functions impact immunity, inflammation, and allergic responses are discussed. CLICK

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Dietary restrictions modulate the gut microbiota: Implications for health and disease

Diet and Exercise, Gut Dysbiosis, Gut Microbiota, Gut Permeability / Leaky Gut, Short Chain Fatty Acids /

The data suggest that changing the gut microbiota composition by dietary restriction has the potential to positively influence the progression of several diseases such as obesity, diabetes, neurological diseases or inflammatory bowel disease. Finally, the relevance of the findings for clinical practice is evaluated and approaches for future research are proposed. CLICK TO REVIEW

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Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris

Biomarkers, Butyrate, Diet and Exercise, Gut Dysbiosis, Gut Microbiota, Gut Permeability / Leaky Gut, Herbs & Spices, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

After in vitro digestion and anaerobic fermentation, both O. sinensis and C. militaris could modulate the gut microbiota composition through reducing the ratio of Firmicutes to Bacteroidetes. Moreover, this research demonstrated that O. sinensis had more positive effects on the intestinalhealth compared with C. militaris via decreasing the pH of gut environment, stimulating the production

Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris Read More »