Diet and Exercise

Natural antioxidants in the management of Parkinson’s disease: review of evidence from cell line and animal models

Anti-oxidants, Diet and Exercise, Parkinson's Disease, Therapies /

Therefore, the use of natural antioxidants in PD may provide an alternative therapy that prevents oxidative stress and reduces disease progression. In this review, the effects of hydroxytyrosol, Ginkgo biloba, Withania somnifera, curcumin, green tea, and Hypericum perforatum in PD animal and cell line models are compared and discussed. The reviewed antioxidants show evidence of protecting neural cells from […]

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Dietary Influences on the Microbiota–Gut–Brain Axis

Diet and Exercise, Gut Dysbiosis, Gut Microbiota, Gut-Brain axis /

Finally, we should revise our view of the gut microbiota from that of a seething mass of microbes to one of organ-status, on which our health and wellbeing utterly depends. Future guidelines on lifestyle strategies for wellbeing should integrate advice on the optimal establishment and maintenance of a healthy gut microbiota through dietary and other

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Investigating the Putative Mechanisms Mediating the Beneficial Effects of Exercise on the Brain and Cognitive Functions

Diet and Exercise, Parkinson's Disease, Pre-PD /

A variety of brain disorders including alzheimer’s disease, parkinson’s disease, chronic stress, age-related cognitive decline, psychological disorders have been revealed to avoid, restore, or improve by different procedures of physical exercise. CLICK TO REVIEW

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Dietary restrictions modulate the gut microbiota: Implications for health and disease

Biomarkers, Butyrate, Diet and Exercise, Gut Permeability / Leaky Gut, Gut-Brain axis /

The data suggests that changing the gut microbiota composition by dietary restriction has the potential to positively influence the progression of several diseases such as obesity, diabetes, neurological diseases or inflammatory bowel disease. Finally, the relevance of the findings for clinical practice is evaluated and approaches for future research are proposed. CLICK TO REVIEW

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Nutritional aspects in Parkinson’s disease

Biomarkers, Diet and Exercise, Parkinson's Disease, Pre-PD /

The links between diet and Parkinson’s disease (PD) are unclear and incomprehensible. However, numerous studies have demonstrated the correlation between diet, nutrients and health condition in PD patients. They indicate the possibility of management of the disease, which might be possible through nutrition. Pharmaceutical treatment as well as a complementary holistic approach to the patients

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Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health

Biomarkers, Diet and Exercise, Gut Microbiota, Gut-Brain axis, Short Chain Fatty Acids /

Animal studies investigating the potential of nutritional interventions on the microbiota–gut–brain axis have led to advancements in our understanding of the role of diet in this bidirectional communication. In this review, we summarize the current state of the literature triangulating diet, microbiota, and host behavior/brain processes and discuss potential underlying mechanisms. Additionally, determinants of the

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New Avenues for Parkinson’s Disease Therapeutics: Disease-Modifying Strategies Based on the Gut Microbiota

Biomarkers, Diet and Exercise, Fecal Transplants (FMT), Probiotics, Prebiotics and Symbiotics /

This review provides status on the different strategies that are in the front line (i.e., antibiotics; probiotics; prebiotics; synbiotics; dietary interventions; fecal microbiota transplantation, live biotherapeutic products), and discusses the opportunities and challenges the field of microbiome research in PD is facing.

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Parkinson’s Disease: Possible Mechanisms for Nutritional Approaches

Diet and Exercise, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics /

Parkinson’s disease (PD) is among the most common chronic neurodegenerative conditions, affecting 1% of those over 60 years of age, and involves motor and non-motor impairments. Alterations in normal physiology may become apparent years – in some cases, 10–20 years – before established diagnostic criteria are met. Thus, better clinical outcomes may result when practitioners

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Boxing with Parkinson’s Disease: findings from a qualitative study using self-determination theory

Diet and Exercise, Parkinson's Disease, Pre-PD /

Adults with Parkinson’s disease (PD) experience debilitating symptoms that may be mitigated by boxing. Yet, attrition from boxing programs is problematic. Understanding whether PD-specific boxing programs can enhance motivation to remain physically active is important. This study investigated adults’ experiences within a PD-specific boxing program and explored their perspectives on how the program has influenced

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