Gut Dysbiosis

Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases

Anti-oxidants, Diet and Exercise, Gut Dysbiosis, Gut Microbiota, Gut Permeability / Leaky Gut, Gut-Brain axis, Parkinson's Disease, Pre-PD, Short Chain Fatty Acids /

The global prevalence of Alzheimer’s disease and Parkinson’s disease is steadily increasing due to the aging population. The lack of effective drugs against these neurodegenerative disorders makes it imperative to identify new strategies for their prevention and treatment. Recent studies have revealed that harnessing the power of the gut microbiota through modification of diet may […]

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The Gut Microbiota Influenced by the Intake of Probiotics and
Functional Foods with Prebiotics Can Sustain Wellness and
Alleviate Certain Ailments like Gut-Inflammation and
Colon-Cancer

Butyrate, Diet and Exercise, Gut Dysbiosis, Gut Permeability / Leaky Gut, Probiotics, Prebiotics and Symbiotics /

The gut microbiota is composed of several microbial strains, with diverse and variablecombinations in healthy and sick persons, changing at different stages of life. A healthy balancebetween host and gut microorganisms must be maintained in order to perform the normal physiological, metabolic, and immune functions and prevent disease development. Disturbances in the balanceof the gut

The Gut Microbiota Influenced by the Intake of Probiotics and
Functional Foods with Prebiotics Can Sustain Wellness and
Alleviate Certain Ailments like Gut-Inflammation and
Colon-Cancer Read More »

Gastrointestinal symptoms of Parkinson’s
disease: A systematic review from pathogenesis
to management

Gut Dysbiosis, Gut-Brain axis, Parkinson's Disease, Pre-PD /

The identification of Parkinson’s disease (PD) is mainly dependent on motorsymptoms, while the non-motor symptoms exist even decades ahead of the PDdiagnosis. According to Braak’s hypothesis, the enteric plexus is the first affectedsite during the pathological development of PD, and gastrointestinal (GI) symptomsappear during the onset of the disease. Although GI symptoms decrease the lifequality

Gastrointestinal symptoms of Parkinson’s
disease: A systematic review from pathogenesis
to management Read More »

The Role of Gut Microbiome and Dysbiosis in Common Psychological,
Neurological, and Behavioral Disorders

Gut Dysbiosis, Gut Microbiota, Gut-Brain axis, Parkinson's Disease, Pre-PD /

According to psychobiotic research expansion, the gut microbiome—a colony of more than 1000 species—is connected to brainhealth and state of mind. Historically, even though a variety of body parts and systems were linked to the nervous system in thenineteenth century, researchers began began researching the gut, especially the stomach, calling it ‘the great abdominal brain’,

The Role of Gut Microbiome and Dysbiosis in Common Psychological,
Neurological, and Behavioral Disorders Read More »

Gastrointestinal symptoms of Parkinson’s
disease: A systematic review from pathogenesis
to management

A-Synuclein, Gut Dysbiosis, Gut Permeability / Leaky Gut, Gut-Brain axis, Parkinson's Disease /

The identification of Parkinson’s disease (PD) is mainly dependent on motorsymptoms, while the non-motor symptoms exist even decades ahead of the PDdiagnosis. According to Braak’s hypothesis, the enteric plexus is the first affectedsite during the pathological development of PD, and gastrointestinal (GI) symptomsappear during the onset of the disease. Although GI symptoms decrease the lifequality

Gastrointestinal symptoms of Parkinson’s
disease: A systematic review from pathogenesis
to management Read More »

Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases

Diet and Exercise, Gut Dysbiosis, Gut Microbiota, Gut-Brain axis, Parkinson's Disease /

The global prevalence of Alzheimer’s disease and Parkinson’s disease is steadily increasing due to the aging population. The lack of effective drugs against these neurodegenerative disorders makes it imperative to identify new strategies for their prevention and treatment. Recent studies have revealed that harnessing the power of the gut microbiota through modification of diet may

Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases Read More »

Gastrointestinal involvement in Parkinson’s disease: pathophysiology, diagnosis, and management

Biomarkers, Constipation, Gut Dysbiosis, Gut Microbiota, Parkinson's Disease /

Growing evidence suggests an increasing significance for the extent of gastrointestinal tract (GIT) dysfunction in Parkinson’s disease (PD). Most patients suffer from GIT symptoms, including dysphagia, sialorrhea, bloating, nausea, vomiting, gastroparesis, and constipation during the disease course. The underlying pathomechanisms of this α-synucleinopathy play an important role in disease development and progression, i.e., early accumulation

Gastrointestinal involvement in Parkinson’s disease: pathophysiology, diagnosis, and management Read More »

Food as Treatment of Inflammatory Bowel Diseases

Butyrate, Diet and Exercise, Gut Dysbiosis, Gut Microbiota /

Inflammatory bowel diseases (IBD), namely, Crohn’s disease (CD) and ulcerative colitis (UC), are lifelong and incurable chronic inflammatory diseases affecting6.8 million people worldwide. By 2030, the prevalence of IBD is estimated to reach 1%of the population in Western countries, and thus there is an urgent need to developeffective therapies to reduce the burden of this

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Dual role of the nasal microbiota in neurological diseases—An unignorable risk factor or a potential therapy carrier

Gut Dysbiosis, Mitochondria, Olfactory, Parkinson's Disease /

Recently, comparative studies have rapidly increased with the closer correlation between microbiota and neurological diseases. However, most insights about the association between microbiota and neurological diseases still focus on the gut-brain axis and ignore that nasal microbiota could form a complex and essential link with the nervous system via the nose-to-brain pathway, suggesting the role

Dual role of the nasal microbiota in neurological diseases—An unignorable risk factor or a potential therapy carrier Read More »