Idiopathic Parkinson’s disease (PD) may take decades to develop, during which many risk or protective factors may come into play to initiate the pathogenesis or modify its progression to clinical PD. The lack of understanding of this prodromal phase of PD and the factors involved has been a major hurdle in the study of PD […]
There is increasing evidence for the important role of gut microbiota (GMB) in the development and progression of neurologic pathologies. Some studies have shown that modifying the microbiome profile can confer benefits to patients. Mild traumatic brain injury (mTBI) is a common occurrence in the general population. Although most patients recover, in a minority, disabling
Objective: The objective of this case study was to elucidate the effect of photobiomodulation (PBM) on the microbiome. Background: The gut microbiome has been identified as a key component of health, with gut dysbiosis, characterized by decreased microbial diversity and an altered microbial composition, being recognized as instrumental in many diseases and disorders. Previous research has suggested
Modifying the Microbiome as a Potential Mechanism of Photobiomodulation: A Case Report Read More »
Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and Creutzfeldt–Jakob disease (CJD) are brain conditions affecting millions of people worldwide. These diseases are associated with the presence of amyloid-β (Aβ), alpha synuclein (α-Syn) and prion protein (PrP) depositions in the brain, respectively, which lead to synaptic disconnection and subsequent progressive neuronal death. Although
IntroductionThere’s a reason we shorten the Standard American Diet to S-A-D. Never has amore fitting abbreviation been seen in the health industry. Our food, and theway our body processes that food, impacts our health in profound ways.And, it all starts in the gut.Put simply, when our gut isn’t healthy and happy, nothing about our bodies
Gut Health Guide; Essential Oils Protocol Read More »
Gastrointestinal dysfunctions represent the most common non-motor symptoms in Parkinson’s disease (PD). Ofnote, changes in gut microbiota, impairments of intestinal epithelial barrier (IEB), bowel inflammation and neuroplastic rearrangements of the enteric nervous system (ENS) could be involved in the pathophysiology of theintestinal disturbances in PD. In this context, although several review articles have pooled together
Gut microbiota is showing and raising evidence that the dynamic changes in the gut microorganism can influence physiology and behavior of brain. Dysbiosis or dysbacteriosis is a condition of microbial imbalance inside the intestinal microbiome. It has been associated with disorders of intestinal and extra‐intestinal such as inflammatory bowel disease and other multiple diseases like
Gut Microbiota-Brain Interaction with Special Reference to Alzheimer’s Disease Read More »
Research has suggested a link between the gut microbiota and Parkinson’s Disease (PD), and an early involvement of gastrointestinal dysfunction has been reported in patients. A mechanism review was performed to investigate whether the neurodegenerative cascade begins in the gut; mediated by gut dysbiosis and retrograde transport of α-synuclein. This review provides a summary of
Two hallmarks of Parkinson’s disease (PD) are the widespread deposition of misfolded alpha-synuclein (αSyn) protein in the nervous system and loss of substantia nigra dopamine neurons. Recent research has suggested that αSyn aggregates in the enteric nervous system (ENS) lead to prodromal gastrointestinal (GI) symptoms such as constipation in PD, then propagating to the brain stem and eventually triggering neurodegeneration and
So what is intestinal permeability? Intestinal permeability (aka ‘leaky gut’) is the condition where the tight junctions on the lining of the intestine loosen, allowing undigested food particles, environmental toxins, foreign bacteria, and other normally restricted molecules to cross the gut barrier and migrate to other parts of the body. Normally, our intestines push molecules
What is leaky gut? Or… what? You can’t even eat HUMMUS? Read More »