Gut Microbiota

Inflammation and immune dysfunction in Parkinson disease

Gut Microbiota, Parkinson's Disease, Pre-PD /

Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral organs as well as the central nervous system and involves a fundamental role of neuroinflammation in its pathophysiology. Neurohistological and neuroimaging studies support the presence of ongoing and end-stage neuroinflammatory processes in PD. Moreover, numerous studies of peripheral blood and cerebrospinal fluid from patients […]

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Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS

Gut Microbiota, Gut-Brain axis /

The recent revelation that the gut microbiome, home to approximately 100 trillion microorganisms, is implicated in the development of both health and disease has spurred an exponential increase in interdisciplinary research involving gut microbiology. In all this hype, there is a need to better understand and contextualize the emerging evidence for the role of the gut microbiota in

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Intertwined Relationship of Mitochondrial Metabolism, Gut
Microbiome and Exercise Potential

Gut Microbiota, Mitochondria /

: The microbiome has emerged as a key player contributing significantly to the humanphysiology over the past decades. The potential microbial niche is largely unexplored in the contextof exercise enhancing capacity and the related mitochondrial functions. Physical exercise can influence the gut microbiota composition and diversity, whereas a sedentary lifestyle in association withdysbiosis can lead

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Microbiome and Exercise Potential Read More »

The gut microbiome and mental health: advances in research and emerging priorities

Gut Dysbiosis, Gut Microbiota, Gut-Brain axis /

The gut microbiome exerts a considerable influence on human neurophysiology and mental health. Interactions between intestinal microbiology and host regulatory systems have now been implicated both in the development of psychiatric conditions and in the efficacy of many common therapies. With the growing acceptance of the role played by the gut microbiome in mental health

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Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS

Biomarkers, Constipation, Gut Microbiota, Gut-Brain axis, Parkinson's Disease, Pre-PD, Vagal Nerve /

The recent revelation that the gut microbiome, home to approximately 100 trillion microorganisms, is implicated in the development of both health and disease has spurred an exponential increase in interdisciplinary research involving gut microbiology. In all this hype, there is a need to better understand and contextualize the emerging evidence for the role of the gut microbiota in

Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS Read More »

Associations between Drinking Water Source and Gut Microbiota Composition in the American Gut Project Database

Butyrate, Gut Microbiota, Short Chain Fatty Acids /

The gut microbiome exerts a fundamental role in host physiology. Extrinsic factors such as lifestyle and diet are widely recognized as the main drivers of gut microbiota composition [1, 2]. While drinking water is among the food items consumed in the largest amount, little is known about its potential impact on gut microbiota structures [3-5]. Objective: We explored

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The Antioxidants Glutathione, Ascorbic Acid and Uric Acid Maintain Butyrate Production by Human Gut Clostridia in The Presence of Oxygen In Vitro

Butyrate, Gut Microbiota, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Uncontrolled oxidative stress, reported in Salmonella and HIV infections, colorectal cancer or severe acute malnutrition, has been associated with anaerobic gut microbiome alteration, impaired butyrate production, mucosal immunity dysregulation and disruption of host-bacterial mutualism. However, the role of major antioxidant molecules in the human body, such as glutathione, ascorbic acid and uric acid, has been neglected in

The Antioxidants Glutathione, Ascorbic Acid and Uric Acid Maintain Butyrate Production by Human Gut Clostridia in The Presence of Oxygen In Vitro Read More »

The Role of Milk Nutrition and Ketogenic Diet in Epileptic
Disorders

Diet and Exercise, Gut Microbiota /

This chapter explores the role of the gut-brain axis, ketogenic diet, and cow’s milk allergy onepileptic seizures, with a special focus on childhood. Milk nutrition is particularly relevant fornormal growth and health in childhood; however, some studies report an association betweencow’s milk allergy and epileptic events. It is necessary to clarify the role of proteinpolymorphisms

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Disorders Read More »

Role of the Gut Microbiome and Its Modulation in Neurodegenerative Diseases

Butyrate, Gut Dysbiosis, Gut Microbiota, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Neurodegenerative disorders are progressive conditions of the central nervous system (CNS), resulting in increased morbidity and mortality. The gut microbiome is a microecosystem that consists of billions of bacteria and fungi, most of which are of good benefit to the human body’s internal milieu via regulating the immune system and controlling the neuronal signals intertwining

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A Critical Review on Health Promoting Benefits of Edible Mushrooms through Gut Microbiota

Diet and Exercise, Gut Microbiota /

Mushrooms have long been used for medicinal and food purposes for over a thousand years, but a complete elucidation of the health-promoting properties of mushrooms through regulating gut microbiota has not yet been fully exploited. Mushrooms comprise a vast, and yet largely untapped, source of powerful new pharmaceutical substances. Mushrooms have been used in health

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