Oral Microbiome

Quantitative and correlational analysis of gut-brain axis in
schizophrenia spectrum and mood disorders

Gut-Brain axis, Oral Microbiome /

The pathophysiology of schizophrenia spectrum disorders and associated mood disordersis complex and highly heterogeneous, suggesting that different molecular pathways are involvedin it. Among those, the microbiome and its connection to the brain (“gut-brain axis”) has emergedas a highly promising research avenue. To evaluate the role of the human microbiome in the gutbrain axis, we evaluated […]

Quantitative and correlational analysis of gut-brain axis in
schizophrenia spectrum and mood disorders Read More »

Research progress on the association of neurological disorders and periodontal diseases

endondonics, Oral Microbiome, Parkinson's Disease, Pre-PD /

Periodontal diseases are inflammatory diseases caused by oral pathogens around the periodontal supporting tissues, leading to systemic and chronic inflammatory conditions. The continuous chronic systemic inflammation may be a trigger of neuroinflammation, which is the prominent feature of a variety of neurological disorders. It implies that there may be a causal link between periodontal diseases

Research progress on the association of neurological disorders and periodontal diseases Read More »

Self-reported periodontitis and C-reactive protein in
Parkinson’s disease: a cross-sectional study of
two American cohorts

endondonics, Oral Microbiome, Parkinson's Disease, Periodontitis, Root Canal /

Periodontitis triggers systemic repercussions, such as elevated levels of high-sensitive C-reactive protein (hs-CRP). This has neverbeen studied within Parkinson’s Disease (PD). The aim of this study is to compare hs-CRP levels of self-reported periodontitis casesversus cases without periodontitis in PD patients. Data from the National Health and Nutrition Examination Survey (2015–2016 and2017–2018 waves) were analyzed.

Self-reported periodontitis and C-reactive protein in
Parkinson’s disease: a cross-sectional study of
two American cohorts Read More »

Facts and controversies regarding oral health in Parkinson’s disease:
A case-control study in Spanish patients

Diet and Exercise, endondonics, Oral Microbiome, Parkinson's Disease, Pre-PD, Root Canal /

Oral disorders are frequent in PD. Good knowledge of these alterations will allow us to design a specific preventive protocol. Some oral alterations may be a sign of diagnostic alert or progression of PD. CLICK TO REVIEW

Facts and controversies regarding oral health in Parkinson’s disease:
A case-control study in Spanish patients Read More »

Roles of oral microbiota and oral-gut microbial transmission in hypertension

Gut-Brain axis, Oral Microbiome, Periodontitis /

Considerable evidence has linked periodontitis (PD) to hypertension (HTN), but the nature behind this connection is unclear. Dysbiosis of oral microbiota leading to PD is known to aggravate different systematic diseases, but the alteration of oral microbiota in HTN and their impacts on blood pressure (BP) remains to be discovered. CLICK TO REVIEW

Roles of oral microbiota and oral-gut microbial transmission in hypertension Read More »

Periodontal inflammatory disease is associated with the risk of Parkinson’s disease: a population-based retrospective matched-cohort study

endondonics, Oral Microbiome, Parkinson's Disease /

Individuals exposed to PID were 1.431 times more likely to develop PD than those who were not exposed. However, future long-term, larger or national data sets combined with genes, environmental exposure, lifestyle changes, dietary habits, and accurately defined PD diagnosis should be investigated to support the current research results. CLICK TO REVIEW

Periodontal inflammatory disease is associated with the risk of Parkinson’s disease: a population-based retrospective matched-cohort study Read More »

Oral microbiomes: more and more importance in oral cavity and whole body

Oral Microbiome, Periodontitis /

Microbes appear in every corner of human life, and microbes affect every aspect of human life. The human oral cavity contains a number of different habitats. Synergy and interaction of variable oral microorganisms help human body against invasion of undesirable stimulation outside. However, imbalance of microbial flora contributes to oral diseases and systemic diseases. Oral microbiomes play

Oral microbiomes: more and more importance in oral cavity and whole body Read More »

Berberine Ameliorates Periodontal Bone Loss by Regulating Gut Microbiota

Butyrate, Oral Microbiome, Periodontitis /

Postmenopausal osteoporosis (PMO) is a risk factor for periodontitis, and current therapeutics against PMO prevent the aggravated alveolar bone loss of periodontitis in estrogen-deficient women. Gut microbiota is recognized as a promising therapeutic target for PMO. Berberine extracted from Chinese medicinal plants has shown its effectiveness in the treatment of metabolic diseases such as obesity

Berberine Ameliorates Periodontal Bone Loss by Regulating Gut Microbiota Read More »

Oral microbiota in human systematic diseases

Oral Microbiome, Periodontitis /

Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The dynamic oral microbiota cooperates with the host to reflect the information and status of immunity and metabolism through two-way communication along the oral cavity and the systemic organs. The oral cavity is one of the most important interaction windows between the

Oral microbiota in human systematic diseases Read More »

Periodontal Pathogens as Risk Factors of Cardiovascular Diseases, Diabetes, Rheumatoid Arthritis, Cancer, and Chronic Obstructive Pulmonary Disease—Is There Cause for Consideration?

Butyrate, Metabolites, Oral Microbiome, Periodontitis, Short Chain Fatty Acids /

Cardiovascular diseases, chronic obstructive pulmonary diseases, diabetes, rheumatoid arthritis, and cancer are the most common noncommunicable diseases (NCDs). These NCDs share risk factors with periodontal disease (PD), a preventable risk factor linked to lifestyle. The discussion regarding the association between these chronic diseases is more complex. There is still a significant knowledge gap particularly of

Periodontal Pathogens as Risk Factors of Cardiovascular Diseases, Diabetes, Rheumatoid Arthritis, Cancer, and Chronic Obstructive Pulmonary Disease—Is There Cause for Consideration? Read More »