Growing evidences show that gut microbiota is associated with the pathogenesis of Parkinson’s disease (PD) and the gut-brain axis can be promising target for the development of the therapeutic strategies for PD. Acupuncture has been used to improve brain functions and inflammation in neurological disorders such as PD, and to recover the gastrointestinal dysfunctions in […]
Periodontal diseases are inflammatory diseases caused by oral pathogens around the periodontal supporting tissues, leading to systemic and chronic inflammatory conditions. The continuous chronic systemic inflammation may be a trigger of neuroinflammation, which is the prominent feature of a variety of neurological disorders. It implies that there may be a causal link between periodontal diseases
Research progress on the association of neurological disorders and periodontal diseases Read More »
Parkinson’s disease (PD) is a neurological disorder associated with severe loss of dopaminergic neurons inthe substantia nigra. These neurons are particularly vulnerable due to increased iron and decreasedantioxidant levels with aging, constant exposure to reactive oxygen species (ROS), and the presence ofneurotoxic compounds. A literature review was compiled and published, in which we postulate that
There are many patients in general practice with health complaints that cannot be medically explained. Some of these patients attribute their health complaints to dental amalgam restorations. This study examined the cost-effectiveness of the removal of amalgam restorations in patients with medically unexplained physical symptoms (MUPS) attributed to amalgam fillings compared to usual care, based
Ischemic eye diseases are major causes of vision impairment. Thus, potential retinoprotective effects of N’N-dimethyltryptamine (DMT) were investigated. To inhibit its rapid breakdown bymonoamine-oxidase A (MAO-A) enzyme, DMT was co-administered with harmaline, a β-carbolinein the Amazonian Ayahuasca brew. Using ligation, 60 min of ischemia was provoked in eyes of rats,followed by 7 days of reperfusion
Therapeutic Properties of Ayahuasca Components in
Ischemia/Reperfusion Injury of the Eye Read More »
New research on the connection between sleep and Parkinson’s disease is being hailed as a “first step” toward curing and preventing the condition, a brain disorder that causes uncontrollable movements. The research, led by the Parkinson’s Progression Markers Initiative, funded by The Michael J. Fox Foundation, is working to make a concrete connection between Parkinson’s and REM sleep
New research reveals sleep disorder may be linked to Parkinson’s Read More »
eople with rapid eye movement (REM) sleep behavior disorder act out their dreams. While sleeping safely in bed, for example, they might throw up their arms to catch an imaginary ball or try to run from an illusory assailant. Such actions are more than just a nuisance. People with the disorder have a 50% to 80% chance
Sleep disorder linked to neurodegeneration aim of NIH-funded grant Read More »
Dietary restriction of carbohydrates has been demonstrated to be beneficial for nervous system dysfunction in animal models and may be beneficial for human chronic pain. The purpose of this review is to assess the impact of a low-carbohydrate/ketogenic diet on the adult nervous system function and inflammatory biomarkers to inform nutritional research for chronic pain.
Microbial dysbiosis in the gut is associated withhuman diseases, and variations in mucus alter gut microbiota.Therefore, we explored the effects of mucin on the gut microbiotausing a community of 19 synthetic gut microbial species. Cultivationof these species in modified Gifu anaerobic medium (GAM)supplemented with mucin before synthetic community assemblyfacilitated substantial growth of the Bacteroides, Akkermansia,and
Parkinson’s disease (PD) is a complex neurodegenerative condition with a multifactorial origin. To date, approaches todrug discovery for PD have resulted in symptomatic therapies for the motor manifestations and signs associated withneurodegeneration but have failed to identify preventive or curative therapies. This failure mainly originates from thepersistence of major gaps in our understanding of the