Periodontitis

Is amalgam removal in patients with medically unexplained physical symptoms cost-effective? A prospective cohort and decision modelling study in Norway

endondonics, Periodontitis, Root Canal /

There are many patients in general practice with health complaints that cannot be medically explained. Some of these patients attribute their health complaints to dental amalgam restorations. This study examined the cost-effectiveness of the removal of amalgam restorations in patients with medically unexplained physical symptoms (MUPS) attributed to amalgam fillings compared to usual care, based […]

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Self-reported periodontitis and C-reactive protein in
Parkinson’s disease: a cross-sectional study of
two American cohorts

endondonics, Oral Microbiome, Parkinson's Disease, Periodontitis, Root Canal /

Periodontitis triggers systemic repercussions, such as elevated levels of high-sensitive C-reactive protein (hs-CRP). This has neverbeen studied within Parkinson’s Disease (PD). The aim of this study is to compare hs-CRP levels of self-reported periodontitis casesversus cases without periodontitis in PD patients. Data from the National Health and Nutrition Examination Survey (2015–2016 and2017–2018 waves) were analyzed.

Self-reported periodontitis and C-reactive protein in
Parkinson’s disease: a cross-sectional study of
two American cohorts Read More »

Roles of oral microbiota and oral-gut microbial transmission in hypertension

Gut-Brain axis, Oral Microbiome, Periodontitis /

Considerable evidence has linked periodontitis (PD) to hypertension (HTN), but the nature behind this connection is unclear. Dysbiosis of oral microbiota leading to PD is known to aggravate different systematic diseases, but the alteration of oral microbiota in HTN and their impacts on blood pressure (BP) remains to be discovered. CLICK TO REVIEW

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Oral microbiomes: more and more importance in oral cavity and whole body

Oral Microbiome, Periodontitis /

Microbes appear in every corner of human life, and microbes affect every aspect of human life. The human oral cavity contains a number of different habitats. Synergy and interaction of variable oral microorganisms help human body against invasion of undesirable stimulation outside. However, imbalance of microbial flora contributes to oral diseases and systemic diseases. Oral microbiomes play

Oral microbiomes: more and more importance in oral cavity and whole body Read More »

Berberine Ameliorates Periodontal Bone Loss by Regulating Gut Microbiota

Butyrate, Oral Microbiome, Periodontitis /

Postmenopausal osteoporosis (PMO) is a risk factor for periodontitis, and current therapeutics against PMO prevent the aggravated alveolar bone loss of periodontitis in estrogen-deficient women. Gut microbiota is recognized as a promising therapeutic target for PMO. Berberine extracted from Chinese medicinal plants has shown its effectiveness in the treatment of metabolic diseases such as obesity

Berberine Ameliorates Periodontal Bone Loss by Regulating Gut Microbiota Read More »

Oral microbiota in human systematic diseases

Oral Microbiome, Periodontitis /

Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The dynamic oral microbiota cooperates with the host to reflect the information and status of immunity and metabolism through two-way communication along the oral cavity and the systemic organs. The oral cavity is one of the most important interaction windows between the

Oral microbiota in human systematic diseases Read More »

Periodontal Pathogens as Risk Factors of Cardiovascular Diseases, Diabetes, Rheumatoid Arthritis, Cancer, and Chronic Obstructive Pulmonary Disease—Is There Cause for Consideration?

Butyrate, Metabolites, Oral Microbiome, Periodontitis, Short Chain Fatty Acids /

Cardiovascular diseases, chronic obstructive pulmonary diseases, diabetes, rheumatoid arthritis, and cancer are the most common noncommunicable diseases (NCDs). These NCDs share risk factors with periodontal disease (PD), a preventable risk factor linked to lifestyle. The discussion regarding the association between these chronic diseases is more complex. There is still a significant knowledge gap particularly of

Periodontal Pathogens as Risk Factors of Cardiovascular Diseases, Diabetes, Rheumatoid Arthritis, Cancer, and Chronic Obstructive Pulmonary Disease—Is There Cause for Consideration? Read More »

Periapical Disease and the Prefrontal Cortex. Is there a Relationship between Calcium-Binding Protein and Neurodegenerative Diseases?

endondonics, Endotoxin, Periodontitis /

Apical periodontitis (AP) or periapical lesion (PL) is an inflammatory disease that causes pain, loss of bone and destruction of other tissues of teeth support. This condition could be caused by caries, dental trauma and/or periapical microleakage wich is regulated by the immune system or inflammatory response. Several analyses have shown that endodontic infection can

Periapical Disease and the Prefrontal Cortex. Is there a Relationship between Calcium-Binding Protein and Neurodegenerative Diseases? Read More »

A Review of Literature on the Relationship Between
Oral Microbiota and Rheumatoid Arthritis

Oral Microbiome, Periodontitis /

Periodontal disease (PDD) and rheumatoid arthritis (RMA) share comparative pathophysiological pathways like ongoingaggravation with resorption of the proximal bone in immunologically delicate hosts; However, PDD has a notable bacteriological etiology, and the cause of RMA remains unknown. According to some reports, an infectious agent in a vulnerable host may be the cause of RMA and

A Review of Literature on the Relationship Between
Oral Microbiota and Rheumatoid Arthritis Read More »

Gingival Crevicular Fluid as Biomarker’s Source for Alzheimer’s Disease

Oral Microbiome, Parkinson's Disease, Periodontitis, Pre-PD, Root Canal /

Periodontitis is a low-grade inflammatory disease caused by a subgingivaldysbiotic microbiota. Multiple studies have determined the higher prevalence of toothloss and poor oral hygiene in patients with Alzheimer’s disease (AD). However, theperiodontal diagnosis, periodontal bacteria or mediators has not been measuredto date. Aim: To determine the periodontal status, the pro-inflammatory mediators,Porphyromonas gingivalis load, and Apoliporpotein

Gingival Crevicular Fluid as Biomarker’s Source for Alzheimer’s Disease Read More »