Probiotics, Prebiotics and Symbiotics

Western and ketogenic diets in neurological disorders: can you tell the difference?

Diet and Exercise, Metabolites, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics /

The prevalence of obesity tripled worldwide between 1975 and 2016, and it is projected that half of the US population will be overweight by 2030. The obesity pandemic is attributed, in part, to the increasing consumption of the high-fat, high-carbohydrate Western diet, which predisposes to the development of the metabolic syndrome and correlates with decreased […]

Western and ketogenic diets in neurological disorders: can you tell the difference? Read More »

Good bacteria, oxidative stress and neurological disorders: Possible therapeutical considerations

Gut Dysbiosis, Gut Microbiota, Probiotics, Prebiotics and Symbiotics /

Although oxidative agents such as free radicals can fight pathogens, an imbalance of oxidants to anti-oxidant activity can lead to harmful effects in our body known as oxidative stress. Various cellular organelles produce oxidative agents as well as anti-oxidants. The main oxidative stressors are classified under the free radical species; reactive oxygen species and reactive

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A Systematic Review on the Effects of Different Types of Probiotics in Animal Alzheimer’s Disease Studies

Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Alzheimer’s disease (AD) is a global public health priority as with aging populations, its prevalence is expected to rise even further in the future. The brain and gut are in close communication through immunological, nervous and hormonal routes, and therefore, probiotics are examined as an option to influence AD hallmarks, such as plaques, tangles, and

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Proof of Concept Study of Prebiotics to Modulate Gut Microbiome in Parkinson’s Disease

Butyrate, Gut Dysbiosis, Gut Permeability / Leaky Gut, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Consumption of a novel prebiotic mixture rapidly impacted the intestinal microbiota (10 days), reduced the abundance of pro-inflammatory bacteria and promoted the growth of beneficial SCFA-producing bacteria. In addition, prebiotic consumption increased plasma SCFA levels, and improved markers of intestinal barrier integrity and brain health. This proof-of-concept study provides evidence for the importance of intestinal

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Mucin modifies microbial composition and improves metabolic
functional potential of a synthetic gut microbial ecosystem

Gut Dysbiosis, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics /

Microbial dysbiosis in the gut is associated withhuman diseases, and variations in mucus alter gut microbiota.Therefore, we explored the effects of mucin on the gut microbiotausing a community of 19 synthetic gut microbial species. Cultivationof these species in modified Gifu anaerobic medium (GAM)supplemented with mucin before synthetic community assemblyfacilitated substantial growth of the Bacteroides, Akkermansia,and

Mucin modifies microbial composition and improves metabolic
functional potential of a synthetic gut microbial ecosystem Read More »

Aging Microbiota-Gut-Brain Axis in Stroke Risk
and Outcome

Gut Dysbiosis, Gut Microbiota, Gut-Brain axis, Probiotics, Prebiotics and Symbiotics, Stroke /

The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut microbes and theirhost. Many environmental and host-related factors affect the gut microbiota. Dysbiosis is defined as compositional andfunctional alterations of the gut microbiota that contribute to the pathogenesis, progression and treatment responses todisease. Dysbiosis occurs when perturbations of microbiota composition and function exceed the ability

Aging Microbiota-Gut-Brain Axis in Stroke Risk
and Outcome Read More »

Modulation of gut health using probiotics: the role of probiotic effector molecules

Gut Microbiota, Gut Permeability / Leaky Gut, Gut-Brain axis, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Probiotics affect intestinal metabolism and play a crucial role in gut homeostasis. Studies on probiotic effector molecules—bacteriocins, peptidoglycan, teichoic acid, exopolysaccharides, secretory proteins, and short-chain fatty acids—describe their effect on the gut barrier; immune and nervous system; and gut microbiota. However, the detailed mechanism of how the intestinal microbiota changes after the intervention of effector

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Fermented brown rice beverage distinctively modulates the gut microbiota in Okinawans with Metabolic Syndrome: a randomized controlled trial

Butyrate, Diet and Exercise, Fermented Foods, Gut Dysbiosis, Gut Microbiota, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Accumulating evidence to date suggests that brown rice is superior to white rice in regards to its beneficial impact on a number of risk factors of the metabolic syndrome (MetS). However, little is known about the influence of fermented brown rice beverage on the gut microbiota in humans. We therefore hypothesized that its impact would

Fermented brown rice beverage distinctively modulates the gut microbiota in Okinawans with Metabolic Syndrome: a randomized controlled trial Read More »

Fermented Foods, Health and the Gut Microbiome

Fermented Foods, Gut Microbiota, Metabolites, Probiotics, Prebiotics and Symbiotics /

Fermented foods have been a part of human diet for almost 10,000 years, and their levelof diversity in the 21st century is substantial. The health benefits of fermented foods have beenintensively investigated; identification of bioactive peptides and microbial metabolites in fermentedfoods that can positively affect human health has consolidated this interest. Each fermented foodtypically hosts

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Probiotics in Health and Disease: A Review of Emerging
Evidence of Potential Benefits and Harm

Gut Dysbiosis, Gut Microbiota, Gut-Brain axis, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics /

Emerging multi-drug resistant pathogens are the main driving force behind the efforts to find analternative treatment approach such as probiotics. Probiotics are considered living drugs that can reduce theconsumption of conventional antibiotics and improve human and animal health. Particularly, bacterial originprobiotics became increasingly popular during the last two decades as a result of the continuously

Probiotics in Health and Disease: A Review of Emerging
Evidence of Potential Benefits and Harm Read More »