Probiotics, Prebiotics and Symbiotics

The potential of human milk oligosaccharides to impact the microbiota-gutbrain axis through modulation of the gut microbiota

Gut Microbiota, Probiotics, Prebiotics and Symbiotics /

ABSTRACT: Human milk oligosaccharides (HMOs) are the first prebiotics humans meet in life. HMOs provide many benefits to infants including impact on gut bacteria, promotion of postnatal brain development, and modulation of the immune system. A complex bidirectional communication pathway called the microbiota-gut-brain axis links gut homeostasis and microbial composition with the central nervous system […]

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Probiotic Bacillus subtilis Protects against a-Synuclein Aggregation in C. elegans

A-Synuclein, Probiotics, Prebiotics and Symbiotics /

Recent discoveries have implicated the gut microbiome in the progression and severity of Parkinson’s disease; however, how gut bacteria affect such neurodegenerative disorders remains unclear. Here, we report that the Bacillus subtilis probiotic strain PXN21 inhibits a synuclein aggregation and clears preformed aggregates in an established Caenorhabditis elegans model of synucleinopathy. CLICK TO REVIEW

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Dysfunction of the Microbiota-Gut-Brain Axis in Neurodegenerative Disease: The Promise of Therapeutic Modulation With Prebiotics, Medicinal Herbs, Probiotics and Synbiotics

Gut Microbiota, Gut-Brain axis, Probiotics, Prebiotics and Symbiotics /

Pre-clinical and human clinical trial data reveal exciting potential for novel treatment targets and therapeutic modulation with prebiotics, medicinal herbs, probiotics, and synbiotics in health, aging, and neurodegeneration and are reviewed here. While greater insights and characterization of the microbiota-gut-brain axis have been revealed over the past decade, salient questions related to the pathology, pathogenesis

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The emerging role of probiotics in neurodegenerative diseases: new hope for Parkinson’s disease?

Probiotics, Prebiotics and Symbiotics /

This review will discuss the potential use of probiotics for Parkinson’s disease prevention or treatment or as adjuvant therapy, confirming that gut microbiota modulation influences different pro-survival pathways. Future investigations in Parkinson’s disease should consider the role of the gut-brain axis and additional comprehension of the underlying mechanisms is extremely necessary. CLICK TO REVIEW

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Faecal Transplantation, Pro- and Prebiotics in Parkinson’s Disease; Hope or Hype?

A-Synuclein, Fecal Transplants (FMT), Probiotics, Prebiotics and Symbiotics /

. Faecal microbiome transplantation (FMT) is an attractive technique, because the administration is relatively simpleand in general has a mild adverse effect pattern. Moreover, FMT consists of a broad mixture, which could be beneficial,because at this moment it is not known what type of changes in the microbiome are needed. However, except from a fewcases

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