Short Chain Fatty Acids

Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Parkinson Disease Patients

A-Synuclein, Butyrate, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

We are grateful for the comment on our study.1 We are pleased to know that short chain fatty acids (SCFA), especially butyrate, in the intestine could stimulate the colonization of curli-producing Escherichia coli (E. coli). Curli are functional amyloids produced by gut microbes and act as cross-beta-sheet amyloid polymers to assist bacterial cells in binding to […]

Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Parkinson Disease Patients Read More »

Impact of Probiotic and Prebiotic on Gut Microbiota in Pre-diabetes and Type 2 Diabetes

Gut Microbiota, Gut-Brain axis, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

The increased worldwide prevalence of pre-diabetes and diabetes, especially type 2 diabetes, requiring different strategies for their prevention and management. A new focus is the reversal of diabetes dysbiosis, a disruption of gut microbiota homeostasis, which is closely related to elevated blood glucose levels and altered metabolic parameters. In this sense, a balanced diet plays a key role, and,

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Gut Microbiota Dysbiosis: Triggers, Consequences, Diagnostic and Therapeutic Options

Butyrate, Fecal Transplants (FMT), Gut Dysbiosis, Gut Microbiota, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

The global incidence of numerous immune-mediated, metabolic, neurodegenerative, and psychiatric diseases is steadily increasing [1,2,3]. The increased morbidity of human populations makes them more vulnerable to additional burdens, including infectious diseases. For example, the mortality rate of diabetics infected with the original variant of the SARS Co-2 virus was about twice that of the general

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Associations between Drinking Water Source and Gut Microbiota Composition in the American Gut Project Database

Butyrate, Gut Microbiota, Short Chain Fatty Acids /

The gut microbiome exerts a fundamental role in host physiology. Extrinsic factors such as lifestyle and diet are widely recognized as the main drivers of gut microbiota composition [1, 2]. While drinking water is among the food items consumed in the largest amount, little is known about its potential impact on gut microbiota structures [3-5]. Objective: We explored

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The Antioxidants Glutathione, Ascorbic Acid and Uric Acid Maintain Butyrate Production by Human Gut Clostridia in The Presence of Oxygen In Vitro

Butyrate, Gut Microbiota, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Uncontrolled oxidative stress, reported in Salmonella and HIV infections, colorectal cancer or severe acute malnutrition, has been associated with anaerobic gut microbiome alteration, impaired butyrate production, mucosal immunity dysregulation and disruption of host-bacterial mutualism. However, the role of major antioxidant molecules in the human body, such as glutathione, ascorbic acid and uric acid, has been neglected in

The Antioxidants Glutathione, Ascorbic Acid and Uric Acid Maintain Butyrate Production by Human Gut Clostridia in The Presence of Oxygen In Vitro Read More »

Periodontal Pathogens as Risk Factors of Cardiovascular Diseases, Diabetes, Rheumatoid Arthritis, Cancer, and Chronic Obstructive Pulmonary Disease—Is There Cause for Consideration?

Butyrate, Metabolites, Oral Microbiome, Periodontitis, Short Chain Fatty Acids /

Cardiovascular diseases, chronic obstructive pulmonary diseases, diabetes, rheumatoid arthritis, and cancer are the most common noncommunicable diseases (NCDs). These NCDs share risk factors with periodontal disease (PD), a preventable risk factor linked to lifestyle. The discussion regarding the association between these chronic diseases is more complex. There is still a significant knowledge gap particularly of

Periodontal Pathogens as Risk Factors of Cardiovascular Diseases, Diabetes, Rheumatoid Arthritis, Cancer, and Chronic Obstructive Pulmonary Disease—Is There Cause for Consideration? Read More »

Role of the Gut Microbiome and Its Modulation in Neurodegenerative Diseases

Butyrate, Gut Dysbiosis, Gut Microbiota, Parkinson's Disease, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Neurodegenerative disorders are progressive conditions of the central nervous system (CNS), resulting in increased morbidity and mortality. The gut microbiome is a microecosystem that consists of billions of bacteria and fungi, most of which are of good benefit to the human body’s internal milieu via regulating the immune system and controlling the neuronal signals intertwining

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Gastrointestinal Microbiome and Neurologic Injury

Butyrate, Constipation, ENS, Fecal Transplants (FMT), Gut Dysbiosis, Gut Microbiota, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

: Communication between the enteric nervous system (ENS) of the gastrointestinal (GI)tract and the central nervous system (CNS) is vital for maintaining systemic homeostasis. Intrinsicand extrinsic neurological inputs of the gut regulate blood flow, peristalsis, hormone release, andimmunological function. The health of the gut microbiome plays a vital role in regulating the overallfunction and well-being

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A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

Butyrate, Gut Dysbiosis, Gut Microbiota, Pre-PD, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

The emerging understanding of gut microbiota as ‘metabolic machinery’ influencing many aspects of physiology has gained substantial attention in the field of psychiatry. This is largely due to the many overlapping pathophysiological mechanisms associated with both the potential functionality of the gut microbiota and the biological mechanisms thought to be underpinning mental disorders. In this

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Gut microbiome alterations in fecal samples of treatment-naïve de novo Parkinson’s disease patients

Gut Dysbiosis, Gut Microbiota, Parkinson's Disease, Pre-PD, Probiotics, Prebiotics and Symbiotics, Short Chain Fatty Acids /

Gut microbiota alterations in Parkinson’s disease (PD) have been found in several studies and are suggested to contribute to the pathogenesis of PD. However, previous results could not be adequately adjusted for a potential confounding effect of PD medication and disease duration, as almost all PD participants were already using dopaminergic medication and were included

Gut microbiome alterations in fecal samples of treatment-naïve de novo Parkinson’s disease patients Read More »