However, no well-powered multicentric trial evaluated the effectiveness of HRW consumption so far in common gastrointestinal diseases with gut flora scenario, including inflammatory bowel disease, irritable bowel syndrome, gastroenteritis and colitis of infectious origin. HRW might be an up-and-coming compound that might tune endogenous H2 homeostasis and modulate gut microbiota but it should still be perceived as an experimental drink and not widely recommended to the general public. CLICK TO REVIEW