Parkinson’s disease (PD) is one of the major progressive neurological disorders. It occurs due to a low level of a
chemical substance in the brain known as Dopamine, which controls the muscle movements of the body. In many cases, PD
occurs due to a low level of dopamine. PD generally appears in persons between the ages of 50 & 60. Some common symptoms of
Parkinson’s are slow movements, tremors, change in voice, depression, anxiety, hallucinations, psychosis, etc. Diagnosis of PD
is done by CAT (Computerized Axial Tomography) scan or MRI (Magnetic Resonance Imaging, and DAT (Dopamine
Transporter) scan. No specific cure for PD but Medication, Surgery, Adequate rest, exercise, and a balanced diet, and Several
different drugs may help to relieve Parkinson’s Disease (PD). According to the in silico study, we found that Rosmarinic Acid
(RA) was the compound, which may inhibit the activities of Sequestosome-1. After in vitro and in vivo studies, Rosmarinic
Acid may be an effective drug to control Parkinson’s disease (PD). CLICK TO REVIEW
Keywords: Parkinson’s, Neurological, Dopamine, Rosmarinic Acid, In silico.