Alzheimer’s disease (AD) is a global public health priority as with aging populations, its prevalence is expected to rise even further in the future. The brain and gut are in close communication through immunological, nervous and hormonal routes, and therefore, probiotics are examined as an option to influence AD hallmarks, such as plaques, tangles, and […]
The global prevalence of Alzheimer’s disease and Parkinson’s disease is steadily increasing due to the aging population. The lack of effective drugs against these neurodegenerative disorders makes it imperative to identify new strategies for their prevention and treatment. Recent studies have revealed that harnessing the power of the gut microbiota through modification of diet may
Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases Read More »
Inflammatory bowel diseases (IBD), namely, Crohn’s disease (CD) and ulcerative colitis (UC), are lifelong and incurable chronic inflammatory diseases affecting6.8 million people worldwide. By 2030, the prevalence of IBD is estimated to reach 1%of the population in Western countries, and thus there is an urgent need to developeffective therapies to reduce the burden of this
Food as Treatment of Inflammatory Bowel Diseases Read More »
Candida spp., Malassezia spp., Cladosporium spp. and Alternaria spp are among the most common fungi detected in the brain of patients with Alzheimer’s disease (AD). These fungi are opportunistic organisms, where they often cause infection among immunocompromised patients. Coincidentally, these fungi can reach the brain and cause fungal meningitis. In general, they enter the brain via systemic infection due to disrupted epithelial
One of the potential benefits of using data-independent acquisition (DIA) proteomics protocols is that information not originally targeted by the study may be present and discovered by subsequent analysis. Herein, we reanalyzed DIA data originally recorded for global proteomic analysis to look for isomerized peptides, which occur as a result of spontaneous chemical modifications to
Psychedelics are increasingly being recognized for their potential to treat a wide range of braindisorders including depression, post-traumatic stress disorder (PTSD), and substance use disorder.Their broad therapeutic potential might result from an ability to rescue cortical atrophy common tomany neuropsychiatric and neurodegenerative diseases by impacting neurotrophic factor geneexpression, activating neuronal growth and survival mechanisms, and
Psychedelic-Inspired Approaches for Treating Neurodegenerative Disorders Read More »