gut-brain

Gut Microbiota and Metabolome Alterations Associated with Parkinson’s Disease

The most significant changes within the Parkinson’s disease group highlighted a reduction in bacterial taxa, which are linked to anti-inflammatory/neu-roprotective effects, particularly in the Lachnospiraceae family and key members,such as Butyrivibrio, Pseudobutyrivibrio, Coprococcus, andBlautia. The direct evalua-tion of fecal metabolites revealed changes in several classes of metabolites. Changeswere seen in lipids (linoleic acid, oleic acid, […]

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Interrelationship between Gut microbiota and Parkinson’s disease

There is a bidirectional communication between the brain and the gut called “gutmicrobiota-brain axis (GMBA)” and its dysfunction causes numerous diseases. This review focuses on theinter-relationship between the gut microbiome and the Parkinson’s disease.(4) (PDF) Interrelationship between Gut microbiota and Parkinson’s disease. Available from: https://www.researchgate.net/publication/346456083_Interrelationship_between_Gut_microbiota_and_Parkinson’s_disease [accessed Jan 31 2021].

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Clinical Phenotypes of Parkinson’s Disease Associate with Distinct Gut Microbiota and Metabolome Enterotypes

We hypothesize that themicrobiota/metabolome enterotypes associated to non-TD subtypes may favor the developmentof gut inflammatory environment and gastrointestinal dysfunctions and therefore a more severeα-synucleinopathy. This study adds important information to PD pathogenesis and emphasizes thepotential pathophysiological link between gut microbiota/metabolites and PD motor subtypes(PDF) Clinical Phenotypes of Parkinson’s Disease Associate with Distinct Gut Microbiota and

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Probiotics : A Dietary Factor to Modulate the Gut Microbiome, Host Immune System, and Gut–Brain Interaction

Abstract: Various benefits of probiotics to the host have been shown in numerous human clinical trials. These organisms have been proposed to act by improving the balance of the gut microbiota and enhancing the production of short-chain fatty acids, as well as by interacting with host cells in the gastrointestinal tract, including immune cells, nerve

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The potential of human milk oligosaccharides to impact the microbiota-gutbrain axis through modulation of the gut microbiota

ABSTRACT: Human milk oligosaccharides (HMOs) are the first prebiotics humans meet in life. HMOs provide many benefits to infants including impact on gut bacteria, promotion of postnatal brain development, and modulation of the immune system. A complex bidirectional communication pathway called the microbiota-gut-brain axis links gut homeostasis and microbial composition with the central nervous system

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Pathophysiology of Parkinson’s disease:
Mitochondria, alpha-synuclein and much more. . .

ABSTRACT: Here, we give an overview of the progress that has been made over the past four decades in our understanding of this disorder. We review the role of mitochondria, environmental toxicants, alpha-synuclein and neuroinflammation in the development of PD. We also discuss more recent data from genetics, which strongly support the endosomal-lysosomal pathways and

Pathophysiology of Parkinson’s disease:
Mitochondria, alpha-synuclein and much more. . .
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