The Role of Dysbiosis in Neurological Disorders

The gut brain axis is a system of bi-directional communication. When the delicate balance of the microbiome is disrupted, the resulting dysbiosis can be a factor in the development of neurological disorders, including Alzheimer’s Disease (AD), Parkinson’s Disease (PK), and Multiple Sclerosis (MS). One major player in the gut brain axis are short-chain fatty acids (SCFA), particularly butyrate, acetate, and propionate. These are produced by key players in the gut microbiome via breakdown of dietary fiber. In this study, we sought to identify a characteristic microbial “signature” of neurological disorders and identify potential therapeutic targets. CLICK TO REVIEW