Netherlands

Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systemic Review

To move from the current heterogeneous dataset towards clinically relevant biomarkers and the identification of putative therapeutic targets, recommendations are derived from the limitations of the available studies to increase the future comparability of microbiome studies in PD. In addition, integration of currently available data on the gut microbiome in PD is proposed to identify […]

Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systemic Review Read More »

Faecal Transplantation, Pro- and Prebiotics in Parkinson’s Disease; Hope or Hype?

. Faecal microbiome transplantation (FMT) is an attractive technique, because the administration is relatively simpleand in general has a mild adverse effect pattern. Moreover, FMT consists of a broad mixture, which could be beneficial,because at this moment it is not known what type of changes in the microbiome are needed. However, except from a fewcases

Faecal Transplantation, Pro- and Prebiotics in Parkinson’s Disease; Hope or Hype? Read More »

Bacterial Metabolites Mirror Altered Gut Microbiota Composition in Patients with Parkinson’s Disease

Increasing evidence is supporting the hypothesis of -synuclein pathology spreading from the gut to the brainalthough the exact etiology of Parkinson’s disease (PD) is unknown. Furthermore, it has been proposed that inflammation,via the gastrointestinal tract, potentially through infections, may contribute to -synuclein pathogenesis, and thus to the riskof developing PD. CLICK TO REVIEW

Bacterial Metabolites Mirror Altered Gut Microbiota Composition in Patients with Parkinson’s Disease Read More »