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Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Chinese herbal medicine treatment based on subgroup differentiation as adjunct therapy for Parkinson’s disease: study protocol of a pilot add-on, randomised, controlled, pragmatic clinical trial
Background Parkinson’s disease (PD) is a prevalent and debilitating condition. Conventional medications cannot control all symptoms and may inflict adverse
Calycosin Alleviates Paraquat-Induced Neurodegeneration by Improving Mitochondrial Functions and Regulating Autophagy in a Drosophila Model of Parkinson’s Disease
first_pagesettingsOpen AccessArticle Calycosin Alleviates Paraquat-Induced Neurodegeneration by Improving Mitochondrial Functions and Regulating Autophagy in a Drosophila Model of Parkinson’s Disease by Hitesh Singh
Gastrointestinal Dysfunction in Parkinson’s Disease
There has been exponential growth in the awareness and understanding of gastrointestinal (GI) dysfunction in Parkinson’s disease (PD) over the
Evolution of Prodromal Multiple System Atrophy from REM Sleep Behavior Disorder: A Descriptive Study
Background:Prodromal multiple system atrophy (MSA) has been characterized mainly by retrospective chart reviews. Direct observation and tracking of prodromal markers
Lactobacillus plantarum DP189 Reduces α-SYN Aggravation in MPTP-Induced Parkinson’s Disease Mice via Regulating Oxidative Damage, Inflammation, and Gut Microbiota Disorder
This study aimed to evaluate the attenuating effect of Lactobacillus plantarum DP189 on α-synuclein (α-SYN) aggregates in the substantia nigra (SN) of
Biomarkers for REM sleep behavior disorder in idiopathic
and narcoleptic patients
To search for discriminating biomarkers, 30 patients with idiopathic rapid-eyemovements sleep behavior disorder (iRBD) were compared with 17 patientswith RBD
Gut Microbiota and Short Chain Fatty Acids: Implications in
Glucose Homeostasis
: Gut microbiota encompasses a wide variety of commensal microorganisms consisting oftrillions of bacteria, fungi, and viruses. This microbial population
Short chain fatty acids: Microbial metabolites for gut-brain axis signalling
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to prominence in recent years.
Mining imaging and clinical data with machine learning approaches for the diagnosis and early detection of Parkinson’s disease
Parkinson’s disease (PD) is a common, progressive, and currently incurable neurodegenerative movement disorder. The diagnosis of PD is challenging, especially
Classifying Idiopathic Rapid Eye Movement Sleep Behavior Disorder, Controls, and Mild Parkinson’s Disease Using Gait Parameters
Gait parameters and a pretrained statistical model can robustly distinguish participants with iRBD from HCs and patients with PD. This
Is the cause of RBD neurological or psychological?
RBD stands for Rapid Eye Movement Disorder and is a sleep disorder that happens duringyour REM (Rapid Eye Movement) stage
Is Fasting Good For Your Brain? The Effects of Fasting on the Brain
Fasting promotes autophagy, a vital recycling process, and stimulates the growth factor BDNF. Autophagy is impaired in neurodegenerative conditions such
Are We What We Eat? Impact of Diet on the Gut–Brain Axis in Parkinson’s Disease
Parkinson’s disease is characterized by motor and non-motor symptoms, such as defects in the gut function, which may occur before
Serum short-chain fatty acids and its correlation with motor and non-motor symptoms in Parkinson’s disease patients
Serum SCFAs are altered in PD patients, and the decrease of serum propionic acid level is correlated with motor symptoms,
Identification of an early-stage Parkinson’s disease neuromarker using event-related potentials, brain network analytics and machine-learning
This pilot study found that BNA can identify patients with early PD using an advanced analysis of ERPs. These results
The second brain in Parkinson’s disease: fact or fantasy?
We have briefly expressed three components that are significant in promoting the complex involvement of the gut within PD. Thorough