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Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Parkinson Disease Patients
Background and Objectives: Short-chain fatty acids (SCFAs) are gut microbial metabolitesthat promote the disease process in a rodent model of
Microbial pathogens induce neurodegeneration in Alzheimer’s disease mice: protection by microglial regulation
Exposure to systemic infections causes neurodegeneration in brain regions displaying amyloid pathology and high local microglia density. AD brains exhibit
A Comprehensive Review on the Role of the Gut Microbiome in Human Neurological Disorders
The human body is full of an extensive number of commensal microbes, consisting of bacteria, viruses, and fungi, collectively termed
Therapeutics in the Pipeline Targeting α-Synuclein for Parkinson’s Disease
Parkinson’s disease (PD) is the second most common neurodegenerative disorder and the fastest growing neurologic disease in the world, yet
Clinical and imaging evidence of brain-first and body-first Parkinson’s disease
Braak’s hypothesis has been extremely influential over the last two decades. However, neuropathological and clinical evidence suggest that the model
A randomised, double-blind, placebo-controlled trial of Bifidobacterium bifidum CCFM16 for manipulation of gut microbiota and relief from chronic constipation
A variety of opinions exist on the potential of probiotics to provide relief from chronic constipation with much focus placed
Serum short-chain fatty acids and its correlation with motor and non-motor symptoms in Parkinson’s disease patients
Serum SCFAs are altered in PD patients, and the decrease of serum propionic acid level is correlated with motor symptoms,
Dairy Intake and Parkinson’s Disease: A Mendelian Randomization Study
Using MR, our findings provide further support for a causal relationship between dairy intake and higher PD risk, not biased
Futuristic food fortification with a balanced ratio of dietary ω-3/ω-6 omega fatty acids for the prevention of lifestyle diseases
Background: Over the last three decades, consumption of total and saturated fat has steadily declined in Western diets as a
Non-Motor Symptoms and Their Associated Factors in Parkinson’s Disease
Background: Parkinson’s disease is a common neurologic ailment that causes tremor and bradykinesia. The prevalenceof Parkinson’s disease is estimated to
MicroRNA Candidate Biomarkers for Parkinson’s Disease and Idiopathic REM Sleep Behavior Disorder
Current study provides a valuable and highly informative dataset of EV-associated sncRNAsfrom plasma of iRBD and PD patients. We identified
Overview on Parkinson’s disease: pathophysiology, and experimental models
Parkinson’s disease, a neurodegenerative disease, is caused by dopaminergic neurons death and accompanied byrigidity, and postural instability, as well as
Physical Activity vs. Redox Balance in the Brain: Brain Health, Aging and Diseases
It has been proven that physical exercise improves cognitive function and memory, hasan analgesic and antidepressant effect, and delays the
Parkinson’s Disease and the Metal–Microbiome–Gut–Brain Axis: A Systems Toxicology Approach
Parkinson’s Disease (PD) is a neurodegenerative disease, leading to motor and nonmotor complications. Autonomic alterations, including gastrointestinal symptoms, precede motordefects
Gut microbiota related to nutrition and physical activity: an integrative review
The gut microbiota (GM) is formed by millions of microorganisms present in the gastrointestinal tract, especially in the colon. This
Homeostatic regulation of neuronal excitability by probiotics in male germ-free mice
Emerging evidence indicates that probiotics can influence the gut–brain axis to ameliorate somatic and behavioral symptoms associated with brain disorders.