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Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Molecular Docking Studies of Secondary Metabolites against Sequestosome-1 to Treat Parkinson Disease
Parkinson’s disease (PD) is one of the major progressive neurological disorders. It occurs due to a low level of achemical
The effect of Tai Chi on functional mobility, balance and falls in Parkinson’s disease: A systematic review and meta-analysis of systematic reviews
Background: The aim of the study was to evaluate the effect of Tai Chi on functional mobility, balance and falls in
Trajectory Analysis of Orthostatic Hypotension in Parkinson’s Disease: Results From Parkinson’s Progression Markers Initiative Cohort
This study provides new information on the longitudinal development of ΔSBP in patients with PD with distinct trajectories of rapidly
Porphyromonas gingivalis indirectly elicits intestinal inflammation by altering the gut microbiota and disrupting epithelial barrier function through IL9-producing CD4+ T cells
Background Recent epidemiological studies have shown that inflammatory bowel disease is associated with periodontal disease. The oral-gut microbiota axis is
Validation of cepstral peak prominence in assessing early voice changes of Parkinson’s disease: Effect of speaking task and ambient noise
ABSTRACT Although the cepstral peak prominence (CPP) and its variant, the cepstral peak prominence smooth (CPPS), are considered to be
Cognition and driving ability in isolated and symptomatic REM sleep behavior disorder
Study Objectives To analyze cognitive deficits leading to unsafe driving in patients with REM Sleep Behavior Disorder (RBD), strongly associated
Environmental triggers of Parkinson’s disease – Implications of the Braak and dual-hit hypotheses
Idiopathic Parkinson’s disease (PD) may take decades to develop, during which many risk or protective factors may come into play
Possible predictors of phenoconversion in isolated REM sleep behaviour disorder: a systematic review and meta-analysis
Background A number of promising biomarkers for predicting imminent α-synucleinopathies have been suggested in isolated rapid eye movement sleep behaviour disorder
A Review of Literature on the Relationship Between
Oral Microbiota and Rheumatoid Arthritis
Periodontal disease (PDD) and rheumatoid arthritis (RMA) share comparative pathophysiological pathways like ongoingaggravation with resorption of the proximal bone in
Disruption of Brainstem Structural Connectivity in REM Sleep Behavior Disorder Using 7 Tesla Magnetic Resonance Imaging
BACKGROUND: Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is one of the earliest manifestations of α synucleinopathies. Brainstem
Relationship between mild traumatic brain injury and the gut microbiome: A scoping review
There is increasing evidence for the important role of gut microbiota (GMB) in the development and progression of neurologic pathologies.
Modifying the Microbiome as a Potential Mechanism of Photobiomodulation: A Case Report
Objective: The objective of this case study was to elucidate the effect of photobiomodulation (PBM) on the microbiome. Background: The gut microbiome
Complex Interaction between Resident Microbiota and Misfolded Proteins: Role in Neuroinflammation and Neurodegeneration
Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and Creutzfeldt–Jakob disease (CJD) are brain conditions affecting millions of
Gut Health Guide; Essential Oils Protocol
IntroductionThere’s a reason we shorten the Standard American Diet to S-A-D. Never has amore fitting abbreviation been seen in the
From the intestinal mucosal barrier to the enteric neuromuscular compartment: An integrated overview on the morphological changes in Parkinson’s disease
Gastrointestinal dysfunctions represent the most common non-motor symptoms in Parkinson’s disease (PD). Ofnote, changes in gut microbiota, impairments of intestinal
Potential Role of Akkermansia muciniphila in Parkinson’s Disease and Other Neurological/Autoimmune Diseases
The composition of the gut microbiota, including Akkermansia muciniphila (A. muciniphila), is altered in many neurological diseases and may be involved in