library
Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Neuropathological evidence of body-first vs. brain-first Lewy body disease
Aggregation of alpha-synuclein into inclusion bodies, termed Lewy pathology, is a defining feature of Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB). In
Clinical therapeutic effects of probiotics in patients with constipation associated with Parkinson disease
Constipation is the most predominant symptom of Parkinson disease (PD), preceding the occurrence of motor symptoms in some patients, leading
Shining light on the head: Photobiomodulation for brain disorders
Photobiomodulation (PBM) describes the use of red or near-infrared light to stimulate, heal, regenerate, and protect tissue that has either
Is Red Light a Missing Nutrient for Our Health? Podcast with Dr. Michael Hamblin
Light is essential to life as we know it. Plants rely upon sunlight to generate chemical energy, which is stored in
Metabolic Strategies in Healthcare: A New Era
Modern healthcare systems are founded on a disease-centric paradigm, which has conferred manynotable successes against infectious disorders in the past.
Short-chain fatty acids as modulators of redox signaling in health and disease
Short-chain fatty acids (SCFAs), produced by colonic bacteria and obtained from the diet, have been linked to beneficial effects on human health
Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease
As tissue macrophages of the central nervous system (CNS), microglia constitute the pivotal immune cells of this organ. Microglial features are strongly dependent on
The role of the host microbiome in autism and neurodegenerative disorders and effect of epigenetic procedures in the brain functions
Autism Spectrum Disorder (ASD) is a severe neurological/neurodegenerative syndrome that results in cognitive and communication disorders. The degree of dysbiosis
Gut Feelings: The Microbiota-Gut-Brain Axis on Steroids
The intricate connection between central and enteric nervous systems is well established with emerging evidence linking gut microbiota function as
Association between CSF alpha-synuclein seeding activity and genetic status in Parkinson’s disease and dementia with Lewy bodies
The clinicopathological heterogeneity in Lewy-body diseases (LBD) highlights the need for pathology-driven biomarkers in-vivo. Misfolded alpha-synuclein (α-Syn) is a lead candidate
Environmental neurotoxicants and inflammasome activation in Parkinson’s disease – a focus on the gut-brain axis
Inflammasomes are multi-protein complexes expressed in immune cells that function as intracellular sensors of environmental, metabolic and cellular stress. Inflammasome
Searching for a Gut-Brain probiotic with real science behind it?
Living with a neurological condition like Parkinson’s disease, autism, or chronic stress is hard enough. It can feel overwhelming to
Effect of Fiber and Fecal Microbiota Transplantation Donor on Recipient Mice Gut Microbiota
Both fecal microbiota transplantation (FMT) and dietary fiber intervention were verified as effective ways to manipulate the gut microbiota, whereas
Microbiota in Health and Disease—Potential Clinical Applications
: Within the last two decades tremendous efforts in biomedicine have been undertaken tounderstand the interplay of commensal bacteria living
$9M Grant Funds Study of Gut-Brain Connection in Parkinson’s Disease
Dr. Michael Kaplitt, a professor of neurological surgery at Weill Cornell Medicine and a longtime leader in developing cutting-edge surgical
CORE ONE LABS’ AKOME SEEKS TO REVOLUTIONIZE TREATMENT OF PARKINSON’S DISEASE AND SUBMITS APPLICATION TO PROTECT IP
Akome’s AKO004 psychedelic drug formulation, for use in the treatment of Parkinson’s disease, is a composition comprising the psychedelic compound