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Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Association of Gut Microbiome Dysbiosis with Neurodegeneration: Can Gut Microbe-Modifying Diet Prevent or Alleviate the Symptoms of Neurodegenerative Diseases?
However, there is limited success in restoring healthy microbial biodiversity in AD and PD patients with general probiotics interventions and
Increased Root Canal Endotoxin Levels are Associated with Chronic Apical Periodontitis, Increased Oxidative and Nitrosative Stress, Major Depression, Severity of Depression, and a Lowered Quality of Life
CAP-related depression was accompanied by increased levels of NOx, LOOH, AOPP, and TRAP. In CAP participants, there was a strong
Clinical and Pre-Clinical Evidence for Enteric α-Synuclein Involvement in Parkinson’s Disease
While commonly attributed to neuronal death in SNpc, postmortem studies have shown α-syn immunoreactivity and LB pathology inthe peripheral, central,
Food for thought: the emerging role of a ketogenic diet in Alzheimer’s disease management
Recently, particular attention has been paid to the possible function of three dietary patterns in AD prevention: the Mediterranean diet,
Modulation of Neuroinflammation by the Gut Microbiota in Prion and Prion-Like Diseases
One fundamental component of systemic homeostasis is the gut microbiota, which communicates withthe CNS via microbial metabolite production, the peripheral
The role of oxidative stress and the underlying biological pathways in the pathogenesis of Parkinson’s Disease
The mechanisms involved in pathogenesis and progression ofPD is not fully understood but there is overwhelming evidence thatmaintenance of redox
Biomonitoring of Mycotoxins in Plasma of Patients with Alzheimer’s and Parkinson’s Disease
In the case of PD, the fact that the disease is accompanied by other non-motor symptoms in organs highly exposed
Comparing the Results from Faecal Microbiome Transplantation (Fmt) and Gut Flora Replacement Therapy (Gfrt) using 16s Mrna Microbiome Mappin
We used the data from 10 randomly chosen patients from our cohort of FMT patients and the same for 10
Cutaneous Alpha-Synuclein is Correlated with Autonomic Impairment in Isolated REM Sleep Behavior Disorder
The presence of p-syn at any biopsy site was correlated with both sympathetic (CASS adrenergic r = 0.6, p <
Dietary patterns affect Parkinson’s disease via the microbiota-gut-brain axis
The Mediterranean diet reduces the risk of PD with favorable alternations of intestinal microbiota, increases levels of SCFAs, and reduces
Early constipation predicts faster dementia onset
in Parkinson’s disease
Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may
Fecal microbiota transplant as a potential treatment for Parkinson’s disease – A case series
In this preliminary uncontrolled case series of 6 PD patients, a treatment with donor FMT infused via colonoscopy, was safe
Influence of probiotic bacteria on gut microbiota composition and gut wall function in an in-vitro model in patients with Parkinson’s disease
In general, the relative proportions of the main bacterial phyla in the microbiotas of PD patients differed from those of
Non-motor symptoms and their use as markers for prodromal and early Parkinson’s Disease
Parkinson’s Disease (PD) is the second most common neurodegenerative disorder. It is a disease with a broad spectrum of symptoms,
Serum and Fecal Markers of Intestinal Inflammation and Intestinal Barrier Permeability Are Elevated in Parkinson’s Disease
Parkinson’s disease (PD) is characterized by alpha-synuclein misfolding with subsequent intraneuronal amyloid formation and accumulation, low grade neuroinflammatory changes, and
The Role of Melatonin and Disrupted Sleep in Neurologic Disorders
Disordered sleep, often linked to abnormal levels of the hormone melatonin, occurs in many if not most neurologic disorders, and