library
Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Colonization of the Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate
Further experiments demonstrated that the beneficial effect of butyrate depended on the bacteria that colonized the gut and that this
Improvement of colonic healing and surgical recovery with perioperative supplementation of inulin and galacto-oligosaccharides
Inulin and GOS diets were associated with increased butyrate production and better anastomotic healing. Histological analysis revealed an enhanced mucosal
Centrally administered butyrate improves gut barrier function, visceral sensation and septic lethality in rats
Short chain fatty acids readily crosses the gut-blood and blood–brain barrier and acts centrally to influence neuronal signaling. We hypothesized
The microbiota-gut-brain axis and Alzheimer disease. From dysbiosis to neurodegeneration: focus on the central nervous system glial cells
Much evidence has accumulated over the past decade in favor of a significant association between dysbiosis, neuroinflammation and neurodegeneration. Presently,
Does modern research validate the ancient wisdom of gut flora and brain connection?
Both animal and human studies evaluating the role of gut dysbiosis on various neurological and neurosurgical diseases, published in peer-reviewed
Diet-Microbiota-Brain Axis in Alzheimer’s Disease
A strong association exists between lifestyle factors and AD prevalence wherein unhealthy dietary factors have been linked to neurodegeneration. Specific
Systematic video-analysis of motor events during REM sleep in idiopathic REM sleep behavior disorder, follow-up and DAT-SPECT
Patients with higher amounts of violent Motor Events had a greater risk of phenoconversion; therefore, their role as a predictor
Gut Microbiome Changes with Osteopathic Treatment of Constipation in Parkinson’s Disease: A Pilot Study
The gut microbiome shifted among individuals with constipation and PD after four weekly treatments with the OMM-sequence. Changes in the
Potential roles of gut microbiota and microbial metabolites in Parkinson’s disease
Parkinson’s disease (PD) is a complicated neurodegenerative disease attributed to multifactorial changes. However, its pathological mechanism remains undetermined. Accumulating evidence
Neuroprotective effects of short-chain fatty acids in MPTP induced mice model of Parkinson’s disease
Finally, the pros and cons of the current treatments for PD, including those targeting microbiota, are assessed. Advancements in research
Do Certain Foods Really Cause Bad Dreams?
I find this article to be quite interesting as they author finds no relationship between dreams and food. This researcher
Air pollution, surrounding green, road proximity and Parkinson’s disease: A prospective cohort study
We found that PM2.5 were associated with increased risk of incident PD while surrounding green was associated with decreased risk of
Parkinson’s is announced long before the diagnosis
Parkinson’s disease is a progressive disease of the brain caused by the death of special nerve cells. The disease is characterized
Gut Microbial Metabolites in Parkinson’s Disease: Implications of Mitochondrial Dysfunction in the Pathogenesis and Treatment
The search for therapeutic targets for Parkinson’s disease (PD) is hindered by the incomplete understanding of the pathophysiology of the
Consistent skin α-synuclein positivity in REM sleep behavior disorder – A two center two-to-four-year follow-up study
Dermal p-syn in iRBD is most probably an early consistent marker of synucleinopathy and may support other indicators of conversion
Neuronal Autophagy: Characteristic Features and Roles in Neuronal Pathophysiology
Autophagy is an important degradative pathway that eliminates misfolded proteins and damaged organelles from cells. Autophagy is crucial for neuronal