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Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Fibroblast growth factor 21 and autophagy: A complex interplay in Parkinson disease
Hence, autophagy modulation might provide some interesting cues for the treatment of PD. Additionally, Fibroblast growth factor 21 (FGF21) which
Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris
After in vitro digestion and anaerobic fermentation, both O. sinensis and C. militaris could modulate the gut microbiota composition through
Natural antioxidants in the management of Parkinson’s disease: review of evidence from cell line and animal models
Therefore, the use of natural antioxidants in PD may provide an alternative therapy that prevents oxidative stress and reduces disease
Is Chelation Therapy a Potential Treatment for Parkinson’s Disease
The current use of chelators in clinical medicine is presented together with a discussion of two clinical trials of PD
Effects of α-Synuclein-Associated Post-Translational Modifications in Parkinson’s Disease
In this Review, we summarize the structure and physiological function of α-syn, and we further highlight the major PTMs (namely
Dietary Influences on the Microbiota–Gut–Brain Axis
Finally, we should revise our view of the gut microbiota from that of a seething mass of microbes to one
Association between Cardiac Autonomic Control and Postural Control in Patients with Parkinson’s Disease
There is an association between the autonomic and postural systems, such that PD patients with blunted cardiac autonomic function in
Biochemical markers for severity and risk in GBA and LRRK2 Parkinson’s disease
Sub-clinical renal impairment is associated with increased likelihood for prodromal PD regardless of genetic status. While the mechanism behind this
Detecting Parkinson’s Disease From an Online Speech-task
Our model performed equally well on data collected in controlled lab environment as well as ‘in the wild’ across different
Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s Disease
Bile acid analysis in the PD appendix reveals an increase in hydrophobic and secondary bile acids, deoxycholic acid (DCA) and
Is Gut Dysbiosis an Epicenter of Parkinson’s Disease?
Nevertheless, the scientific literature is overflowing with the remarkable observations supporting the role of dysbiosis in PD. Lack of specificity
Identification of novel biomarkers for Parkinson’s disease by metabolomic technologies
Metabolomic analysis detected biomarkers associated with PD pathogenesis and disease progression. Since critical metabolic biomarkers need to be identified in
The Gut-Brain Axis
The concept of the gut-brain axis (GBA) has existed for more than 3 decades [1]. Gastrointestinal motor and sensory components
The Relationship of Rapid Eye Movement Sleep Behavior Disorder and Freezing of Gait in Parkinson’s Disease
The neural changes were seen in PD with FOG and RBD, and sensory and motor changes observed in these two
Prevalence of idiopathic REM behavior disorder: a systematic review and meta-analysis
Prevalence estimates of iRBD are significantly impacted by diagnostic level of certainty. Variations in pRBD prevalence are due to methodological
Role of the Intestinal Microbiome, Intestinal Barrier and Psychobiotics in Depression
Additionally, it is known that, in periods of excessive activation of stress reactions, the immune system also plays an important