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Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Physical activity profiles in Parkinson’s disease
Conclusion: Distinct PA profiles, with clear differences in how the time awake is spent exist among people withmild-moderate PD. CLICK
Development of early diagnosis of Parkinson’s disease and comprehensive economic analysis of the effect of its implementation
This approach can also be used to verify blood markers identified in patients at the clinical stage of PD. It
Parkinson’s disease in a worker exposed to insecticides at a greenhouse
In this case, the field study and epidemiological results supported the work-relatedness of PD and exposure to pesticides. Moreover, the
Parkinson’s Disease: Alterations in Iron and Redox Biology as a Key to Unlock Therapeutic Strategies
This dysfunction could then drive alterations in iron trafficking that attempt to rescue energy deficits such as the increased iron
Lower lymphocyte count is associated with increased risk of Parkinson’s disease
We provide converging evidence from observational analyses in UKB and MR that lower lymphocyte count is associated with an increased
The Relationship of Rapid Eye Movement Sleep Behavior Disorder and Freezing of Gait in Parkinson’s Disease
Rapid eye movement sleep behavior disorder (RBD) contributes to injury due to the alteration of the expected atonia during rapid
Spectrum of Non-Motor Symptoms in Parkinson’s Disease
Parkinson’s disease is predominantly classified as a movement disorder. Beyond the textbook definition of rigidity, tremors, and bradykinesia, Parkinson’s disease
Eye Exam Could Lead to Early Parkinson’s Disease Diagnosis
A simple eye exam combined with powerful artificial intelligence (AI) machine learning technology could provide early detection of Parkinson’s disease,
Central retina changes in Parkinson’s disease: a systematic review and meta‑analysis
Conclusion The whole thickness, the thickness of the combination of ganglion cell layer and inner plexiform layer, and nervefiber layer
REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing BAC-transgenic mouse model
Finally, decreased α-synuclein oligomer accumulation and mitochondrial dysfunction in mice correlated with nuclear REST and PGC-1α in protected SN GABAergic
Clinical characteristics of newly diagnosed Parkinson’s disease patients included in the longitudinal BIO-PD study
The frequencies of symptoms and abnormal findings in PD patients were as follows: hyposmia 82.4%, substantia nigra hyperechogenicity 75.4%, history
Effects of Resistant Starch on Symptoms, Fecal Markers and Gut Microbiota in Parkinson’s Disease – The RESISTA-PD Trial
Clinically, we observed a reduction in non-motor symptoms load in PD + RS. The reference-based analysis of metagenomes highlighted stable
A narrative review of relationship between gut microbiota and neuropsychiatric disorders: mechanisms and clinical application of probiotics and prebiotics
Current research shows that probiotics and prebiotics have a good preventive effect on Alzheimer’s disease, Parkinson’s disease, depression, autism spectrum
Why Researchers Look to Gut Microbial Metabolites in Parkinson’s Disease
Findings highlight significant differences in the fecal microbiome and metabolome in patients with Parkinson’s disease and control subjects, demonstrating an
Gastrointestinal dysfunction in movement disorders
This article provides an overview of the clinical presentation, investigations, and treatment options for gastrointestinal tract (GIT) dysfunction in patients
Smell tests to distinguish Parkinson’s disease from other neurological disorders: a systematic review and meta-analysis
Olfactory impairment has been considered for differential diagnosis in Parkinson’s Disease (PD) patients. The authors aimed to identify the tests