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Research
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Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Prebiotic dietary fibre intervention improves fecal markers related to inflammation in obese patients: results from the Food4Gut randomized placebo-controlled trial
Our study demonstrates that ITF-prebiotic intake during 3 months decreases a fecal marker of intestinal inflammation in obese patients. Our data
Gut Microbial Ecosystem in Parkinson Disease: New Clinicobiological Insights from Multi‐Omics
Gut microbiome alterations in Parkinson disease (PD) have been reported repeatedly, but their functional relevance remains unclear. Fecal metabolomics, which
Marker-free imaging of α-Synuclein aggregates in a rat model of
2 Parkinson’s disease using Raman microspectroscopy
A hallmark of Parkinson’s disease (PD) is the formation of Lewy bodies in the brain. Lewy bodies are rich in
Advances of Mechanisms-Related Metabolomics in Parkinson’s Disease
In this review, we briefly summarize recent findings and analyze the application of molecular metabolomics in familial and sporadic PD
PREMOTOR PARKINSON’S DISEASE: OVERVIEW OF CLINICAL SYMPTOMS AND CURRENT DIAGNOSTIC METHODS
The best known premotor symptoms include hyposmia, REM sleep behavior disorder (RBD), constipation, and depression; other symptoms are excessive daytime
Gastrointestinal Dysfunction in Parkinson’s Disease
Here, we summarize the types and prevalence of subjective gastrointestinal symptoms and objective dysfunction in PD. The potential importance of
Rapid Eye Movement (REM) Sleep Behavior Disorder
REM sleep behaviour disorder overwhelmingly affects males older than 50 years, but increasingly this disorder is being identified in females
Neuroprotective potential of cinnamon and its metabolites in Parkinson’s disease: Mechanistic insights, limitations, and novel therapeutic opportunities
In addition, in vitro and in vivo studies have shown that cinnamon extracts may affect the oligomerization process and aggregation
Clinical and neuroendocrinological characteristics of delayed orthostatic hypotension in Parkinson’s disease
Compared with patients without OH, patients with DOH had severe hyposmia. Relatively preserved peripheral sympathetic nervous system function in patients
Use of Shotgun Metagenomics and Metabolomics to Evaluate the Impact of Glyphosate or Roundup MON 52276 on the Gut Microbiota and Serum Metabolome of Sprague-Dawley Rats
In conclusion, the present study demonstrates the power of using multi-omics molecular profiling to reveal changes in the gut microbiome
Towards subgroup-specific risk estimates: A meta-analysis of longitudinal studies on olfactory dysfunction and risk of Parkinson’s disease.
The presence of olfactory dysfunction conveys a considerably elevated risk of incident PD, likely more in studies with a higher
Intermittent Fasting Alleviates Cognitive Impairments and Hippocampal Neuronal Loss but Enhances Astrocytosis in Mice with Subcortical Vascular Dementia
The improvements in SVaD-IF mice suggest that IF could be a potential nonpharmacological remedy for SVaD. This finding could stimulate
The human olfactory system in two proteinopathies: Alzheimer’s and Parkinson’s diseases
Connectomic approaches reveal a number of hubs in the olfactory system (anterior olfactory nucleus, olfactory entorhinal cortex and cortical amygdala)
Benefits under the Sea: The Role of Marine Compounds in Neurodegenerative Disorders
This review will focus on the most promising marine drugs’ neuro-protective potential for neuro-degenerative disorders, such as Parkinson’s and Alzheimer’s
Gut Microbiota and Metabolome Alterations Associated with Parkinson’s Disease
The most significant changes within the Parkinson’s disease group highlighted a reduction in bacterial taxa, which are linked to anti-inflammatory/neu-roprotective
Interrelationship between Gut microbiota and Parkinson’s disease
There is a bidirectional communication between the brain and the gut called “gutmicrobiota-brain axis (GMBA)” and its dysfunction causes numerous