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Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Clinical Phenotypes of Parkinson’s Disease Associate with Distinct Gut Microbiota and Metabolome Enterotypes
We hypothesize that themicrobiota/metabolome enterotypes associated to non-TD subtypes may favor the developmentof gut inflammatory environment and gastrointestinal dysfunctions and
Feast then famine – how fasting might make our cells more resilient to stress
Intermittent fasting (also called alternate day fasting) has become a popular diet. In most versions of intermittent fasting, people fast or
Exercise-Mediated Neurogenesis in the Hippocampus via BDNF
As a member of the neurotrophin family, BDNF regulates many of the processes within neurogenesis, such as differentiation and survival.
Hydrogen-rich water as a modulator of gut microbiota?
However, no well-powered multicentric trial evaluated the effectiveness of HRW consumption so far in common gastrointestinal diseases with gut flora
Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain
Gut dysbacteriosis is closely related to various intestinal and extraintestinal diseases. Fecal microbiota transplantation (FMT) is a biological therapy that
Expression Levels of an Alpha-Synuclein Transcript in Blood May Distinguish between Early Dementia with Lewy Bodies and Parkinson’s Disease
In conclusion, SNCA transcripts showed a disease-specific increase in the brain and were diminished in blood of LBD patients. SNCAtv3
Alpha-Synuclein: The Interplay of Pathology, Neuroinflammation, and Environmental Factors in Parkinson’s Disease
Background: Parkinson’s disease (PD) is a multifactorial, chronic, and progressive neurodegenerative disease. α-Synuclein (α-syn), which is the main protein component of
The Mitochondrial Permeability Transition: Nexus of Aging, Disease and Longevity
The increased activity of mPTP in aging turns autophagy/mitophagy into a destructive process leading to cell aging and death. Several
Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain
We have reviewed the latest research on the role of gut microbiota in different nervous system diseases as well as
Achieving brain clearance and preventing neurodegenerative diseases—A glymphatic perspective
The glymphatic system is involved in clearance of metabolic byproducts such as amyloid-b from the brain, and its function is
Top 10 Foods to Boost Your BDNF
BDNF (the acronym for brain-derived neurotrophic factor) is a protein produced in high quantities in the central nervous system. It
Brain-derived neurotrophic factor (BDNF)
Brain-derived neurotrophic factor, or BDNF, is a growth factor with broad relevance for aging, brain function, behavior, metabolism, energy expenditure,
Top 33 Tips to Optimize Your Sleep Routine
Sleep is one of the great mysteries of life. For a long time, it was widely thought that sleep was
How microcompetition with latent viruses can cause α synuclein aggregation, mitochondrial dysfunction, and eventually Parkinson’s disease
The cause of most Parkinson’s disease cases is unknown. However, it is well documented that mitochondrial dysfunction and misfolded α synuclein aggregation
Be well: A potential role for vitamin B in COVID-19
There is a need to highlight the importance of vitamin B because it plays a pivotal role in cell functioning,
Longitudinal analysis of premotor anthropometric and serological markers of Parkinson’s disease
Parkinson’s disease (PD) is a debilitating neurodegenerative disorder in which nonmotor symptoms, such as constipation and hyposmia, precede the onset