library
Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Over 200 Scientists & Doctors Call For Increased Vitamin D Use To Combat COVID-19
Research shows low vitamin D levels almost certainly promote COVID-19 infections, hospitalizations, and deaths. Given its safety, we call for
Role of dietary fiber in the recovery of the human gut microbiome and its metabolome
The impact of diet, particularly fiber, on the human microbiome influences broad classes of metabolites that may modify health. CLICK
Acupoint Massage Therapy Alters the Composition of Gut Microbiome in Functional Constipation Patients
The 16S KEGG function prediction suggested that Parkinson disease, retinol metabolism, and arachidonic acid metabolism could explain the biological function
Evolution of the Human Diet and Its Impact on Gut Microbiota, Immune Responses, and Brain Health
Given the tremendous amount of evidence linking neuroinflammation with neural dysfunction, it is no surprise that the Western diet has
Physical activity as a mediator of anxiety and cognitive functioning in Parkinson’s disease
Analyses revealed a significant direct effect of anxiety predicting cognitive functioning. Additionally, there was a significant indirect within-person effect; meaning
Olfactory impairment as an early marker of Parkinson’s disease in REM sleep behavior disorder: a systematic review and meta-analysis
We identified similar olfactory impairments in patients with RBD and patients with PD (either with or without underlying RBD). These
Probiotics : A Dietary Factor to Modulate the Gut Microbiome, Host Immune System, and Gut–Brain Interaction
Abstract: Various benefits of probiotics to the host have been shown in numerous human clinical trials. These organisms have been
The potential of human milk oligosaccharides to impact the microbiota-gutbrain axis through modulation of the gut microbiota
ABSTRACT: Human milk oligosaccharides (HMOs) are the first prebiotics humans meet in life. HMOs provide many benefits to infants including
Probiotic Bacillus subtilis Protects against a-Synuclein Aggregation in C. elegans
Recent discoveries have implicated the gut microbiome in the progression and severity of Parkinson’s disease; however, how gut bacteria affect
Pathophysiology of Parkinson’s disease:
Mitochondria, alpha-synuclein and much more. . .
ABSTRACT: Here, we give an overview of the progress that has been made over the past four decades in our
A discrete glycinergic neuronal population in the ventromedial medulla that induces muscle atonia during REM sleep and cataplexy in mice
During rapid eye movement (REM) sleep, anti-gravity muscle tone and bodily movements are mostly absent, because somatic motoneurons are inhibited
THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON’S DISEASE
Based on both clinical and neuropathological data, PD, traditionally accepted as a dopaminergic motor disorder, now can be characterized as
Gut microbiota: a potential therapeutic target for Parkinson’s disease
If therapeutic manipulation of gut microbiota proves effective to treat some pathogenic aspects of PD, an important inquiry would be
Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systemic Review
To move from the current heterogeneous dataset towards clinically relevant biomarkers and the identification of putative therapeutic targets, recommendations are
Effects of dietary restriction on neuroinflammation in neurodegenerative diseases
Chronic or intermittent food restriction has profound effects in shaping brain and peripheral metabolism, immunity, and gut microbiome biology. Interactions
Dysfunction of the Microbiota-Gut-Brain Axis in Neurodegenerative Disease: The Promise of Therapeutic Modulation With Prebiotics, Medicinal Herbs, Probiotics and Synbiotics
Pre-clinical and human clinical trial data reveal exciting potential for novel treatment targets and therapeutic modulation with prebiotics, medicinal herbs,