library
Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Positive Interventional Effect of Engineered Butyrate-Producing
Bacteria on Metabolic Disorders and Intestinal Flora Disruption
in Obese Mice
The substantially increased prevalence of obesity and obesity-relateddiseases has generated considerable concern. Currently, synthetic biological strategieshave played an essential role
Roles of oral microbiota and oral-gut microbial transmission in hypertension
Considerable evidence has linked periodontitis (PD) to hypertension (HTN), but the nature behind this connection is unclear. Dysbiosis of oral
Dual role of the nasal microbiota in neurological diseases—An unignorable risk factor or a potential therapy carrier
Recently, comparative studies have rapidly increased with the closer correlation between microbiota and neurological diseases. However, most insights about the
Metagenomic and Functional Characterization of Two Chilean
Kefir Beverages Reveals a Dairy Beverage Containing Active
Enzymes, Short-Chain Fatty Acids, Microbial β-Amyloids,
and Bio-Film Inhibitors
: Kefir beverage is a probiotic food associated with health benefits, containing probioticmicroorganisms and biomolecules produced during fermentation. The microbial
Effects of Cannabidiol on Parkinson’s Disease in a Transgenic Mouse Model by Gut-Brain Metabolic Analysis
Parkinson’s disease (PD) is a common neurodegenerative disease characterized by a disorder of the dopaminergic system in the midbrain, causing
Effect of fermented foods on some neurological diseases, microbiota, behaviors: mini review
Fermented foods are among the traditional foods consumed for centuries. In recent years, awareness of fermented foods has been increasing
Dietary manipulation of the gut microbiome in inflammatory bowel disease
patients: Pilot study
Diet is a modifiable, noninvasive, inexpensive behavior that is crucial in shaping the intestinalmicrobiome. A microbiome “imbalance” or dysbiosis in
Alpha-Synuclein-Specific Naturally Occurring Antibodies
Inhibit Aggregation In Vitro and In Vivo
Parkinson’s disease (PD) is associated with motor and non-motor symptoms and characterized by aggregates of alpha-synuclein (αSyn). Naturally occurring antibodies
Cellular and Molecular Events Leading to Paraquat-Induced Apoptosis: Mechanistic Insights into Parkinson’s Disease Pathophysiology
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the cardinal features of tremor, bradykinesia, rigidity, and postural instability,
Bacteria-Derived Protein Aggregates Contribute to the Disruption of Host Proteostasis
Neurodegenerative protein conformational diseases are characterized by misfolding and aggregation of metastable proteins encoded within the host genome. The host
Psychobiotics in Health, Longevity, and Neurological Disorders
Psychobiotics are an emerging class of probiotics that, when ingested in ample amounts, confer mental health benefits through interacting with
Butyrate Inhibits Osteoclast Activity In Vitro and Regulates Systemic Inflammation and Bone Healing in a Murine Osteotomy Model Compared to Antibiotic-Treated Mice
Short-chain fatty acids (SCFAs) produced by the gut microbiota have previously been demonstrated to play a role in numerous chronic
Alpha-synuclein as a Potential Biomarker for Parkinson’s Disease and Other
Synucleinopathies: Gaps, Challenges, and Opportunities
Parkinson’s disease (PD), the second most common progressive neurodegenerative disease,develops and progresses for 10-15 years before the clinical diagnostic symptoms
Periodontal inflammatory disease is associated with the risk of Parkinson’s disease: a population-based retrospective matched-cohort study
Individuals exposed to PID were 1.431 times more likely to develop PD than those who were not exposed. However, future
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
The cellular hallmarks of Parkinson’s disease (PD) are the loss of nigral dopaminergic neurons and the formation of α-synuclein-enriched Lewy
Hydrogen Sulfide Produced by Gut Bacteria May Induce Parkinson’s Disease
Several bacterial species can generate hydrogen sulfide (H2S). Study evidence favors the view that the microbiome of the colon harbors