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Research
Information is knowledge
Information is the most powerful tool in existance and it is my desire to share with our community everything I encounter on my journey to find a solution to Pre-PD and iRBD.
Inflammation and immune dysfunction in Parkinson disease
Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral organs as well as the central nervous system and
Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS
The recent revelation that the gut microbiome, home to approximately 100 trillion microorganisms, is implicated in the development of both health
Behavioral validation of the University of Michigan REM behavior disorder questionnaire in the synucleinopathies
Many questionnaires have been proposed to collect data related to dream enactment. These are typically validated by reference to objective
Intertwined Relationship of Mitochondrial Metabolism, Gut
Microbiome and Exercise Potential
: The microbiome has emerged as a key player contributing significantly to the humanphysiology over the past decades. The potential
The gut microbiome and mental health: advances in research and emerging priorities
The gut microbiome exerts a considerable influence on human neurophysiology and mental health. Interactions between intestinal microbiology and host regulatory
Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS
The recent revelation that the gut microbiome, home to approximately 100 trillion microorganisms, is implicated in the development of both health
Associations between Drinking Water Source and Gut Microbiota Composition in the American Gut Project Database
The gut microbiome exerts a fundamental role in host physiology. Extrinsic factors such as lifestyle and diet are widely recognized
The Antioxidants Glutathione, Ascorbic Acid and Uric Acid Maintain Butyrate Production by Human Gut Clostridia in The Presence of Oxygen In Vitro
Uncontrolled oxidative stress, reported in Salmonella and HIV infections, colorectal cancer or severe acute malnutrition, has been associated with anaerobic gut microbiome
Oral microbiomes: more and more importance in oral cavity and whole body
Microbes appear in every corner of human life, and microbes affect every aspect of human life. The human oral cavity
Berberine Ameliorates Periodontal Bone Loss by Regulating Gut Microbiota
Postmenopausal osteoporosis (PMO) is a risk factor for periodontitis, and current therapeutics against PMO prevent the aggravated alveolar bone loss
Oral microbiota in human systematic diseases
Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The dynamic oral microbiota cooperates with the
Periodontal Pathogens as Risk Factors of Cardiovascular Diseases, Diabetes, Rheumatoid Arthritis, Cancer, and Chronic Obstructive Pulmonary Disease—Is There Cause for Consideration?
Cardiovascular diseases, chronic obstructive pulmonary diseases, diabetes, rheumatoid arthritis, and cancer are the most common noncommunicable diseases (NCDs). These NCDs
The Role of Milk Nutrition and Ketogenic Diet in Epileptic
Disorders
This chapter explores the role of the gut-brain axis, ketogenic diet, and cow’s milk allergy onepileptic seizures, with a special
Effects of Intermittent Fasting On Cognition and
Neurodegeneration
Intermittent fasting (IF) can facilitate neurodegenerative, neuroadaptive and neuroprotective processes leading toprofound effects on cognition and dementias. The impact that
Role of the Gut Microbiome and Its Modulation in Neurodegenerative Diseases
Neurodegenerative disorders are progressive conditions of the central nervous system (CNS), resulting in increased morbidity and mortality. The gut microbiome
Impact of Two Neuronal Sigma-1 Receptor Modulators, PRE084
and DMT, on Neurogenesis and Neuroinflammation in an
Aβ1-42-Injected, Wild-Type Mouse Model of AD
Alzheimer’s disease (AD) is the most common form of dementia characterized by cognitivedysfunctions. Pharmacological interventions to slow the progression of